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Catalog No: OPCD07060
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OPCD07060
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Datasheets/ManualsPrintable datasheet for SMAD1 Recombinant Protein (OPCD07060)
Product Info
Predicted Species ReactivityRat|Rattus norvegicus
Product FormatFreeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
HostE.coli
ConjugationUnconjugated
ApplicationPositive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Additional InformationEndotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
::Residues: His273-Ser468
Reconstitution and Storage2°C to 8°C|-80°C
Concentration200 ug/mL (prior to lyoph)
Purity> 95%
SourceE.coli
TagN-terminal His Tag
Gene SymbolSmad1
Gene Full NameSMAD family member 1
Alias SymbolsMAD (mothers against decapentaplegic, Drosophila) homolog 1;MAD homolog 1;MAD homolog1 (mothers against decapentaplegic, Drosophila);Madh1;mothers against decapentaplegic homolog 1;mothers against DPP homolog 1;SMAD 1;SMAD family member 1;SMAD, mothers against DPP homolog 1.
NCBI Gene Id25671
Protein NameMothers against decapentaplegic homolog 1
Description of TargetTranscriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD). Has been shown to be also activated by TGF-beta (transforming growth factor) type I receptor kinase in rat intestinal epithelial cells (IEC 4-1). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression (By similarity).
Uniprot IDP97588
Protein Size (# AA)His273~Ser468
Molecular Weight23.41kDa
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