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Catalog No: OPCD07040
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OPCD07040
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Datasheets/ManualsPrintable datasheet for SLIT1 Recombinant Protein (OPCD07040)
Product Info
Predicted Species ReactivityHomo sapiens|Human
Product FormatFreeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
HostE.coli
ConjugationUnconjugated
ApplicationPositive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Additional InformationEndotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
::Residues: Asn647-Arg835
Reconstitution and Storage2°C to 8°C|-80°C
Concentration200 ug/mL (prior to lyoph)
Purity> 95%
SourceE.coli
TagN-terminal His Tag
Gene SymbolSLIT1
Gene Full Nameslit guidance ligand 1
Alias SymbolsMEGF4;multiple EGF-like domains protein 4;multiple epidermal growth factor-like domains protein 4;SLIL1;slit homolog 1;slit homolog 1 protein;SLIT-1;SLIT3.
NCBI Gene Id6585
Protein NameSlit homolog 1 protein
Description of TargetThought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions (By similarity). SLIT1 and SLIT2 together seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb.
Uniprot IDO75093
Protein Accession #NP_003052.2
Nucleotide Accession #NM_003061.2
Protein Size (# AA)Asn647~Arg835
Molecular Weight24kDa
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