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Catalog No: OPCD06920
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OPCD06920
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Datasheets/ManualsPrintable datasheet for SLC6A4 Recombinant Protein (OPCD06920)
Product Info
Predicted Species ReactivityHomo sapiens|Human
Product FormatFreeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
ConjugationUnconjugated
ApplicationPositive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Additional InformationEndotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
Residues: Ala181-Ser252
Isoelectric Point: 6.2
Subcellular Location: Chromosome.
Reconstitution and Storage2°C to 8°C|-80°C
Concentration150 ug/mL (prior to lyoph)
Purity> 97%
SourceE.coli
TagN-terminal His and GST Tag
Gene SymbolSLC6A4
Gene Full Namesolute carrier family 6 member 4
Alias Symbols5HT transporter;5HTT;5-HTT;5-HTTLPR;5-hydroxytryptamine (serotonin) transporter;hSERT;HTT;Na+/Cl- dependent serotonin transporter;OCD1;serotonin transporter 1;SERT;SERT1;sodium-dependent serotonin transporter;solute carrier family 6 (neurotransmitter transporter), member 4;solute carrier family 6 (neurotransmitter transporter, serotonin), member 4;Solute carrier family 6 member 4.
NCBI Gene Id6532
Protein NameSodium-dependent serotonin transporter
Description of TargetSerotonin transporter whose primary function in the central nervous system involves the regulation of serotonergic signaling via transport of serotonin molecules from the synaptic cleft back into the pre-synaptic terminal for re-utilization. Plays a key role in mediating regulation of the availability of serotonin to other receptors of serotonergic systems. Terminates the action of serotonin and recycles it in a sodium-dependent manner.
Uniprot IDP31645
Protein Accession #NP_001036.1
Nucleotide Accession #NM_001045.5
Protein Size (# AA)Ala181~Ser252
Molecular Weight38kDa
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