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Catalog No: OABF01657
Size:100UL
Price: $438.00
SKU
OABF01657
Availability: 3 to 5 business days.
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  • $55: Antibody & Protein in US
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Datasheets/ManualsPrintable datasheet for SLC5A8 Antibody (OABF01657)
Product Info
Predicted Species ReactivityBovine|Chicken|Dog|Human|Mouse|Rat
Product FormatLiquid. Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.
ClonalityPolyclonal
IsotypeIgG
HostRabbit
ConjugationUnconjugated
ApplicationEnzyme-linked immunosorbent assay|Immunohistochemistry-Paraffin|Western blot
Additional InformationSubcellular location: Extracellular.
Reconstitution and Storage-20°C
ImmunogenKLH conjugated synthetic peptide derived from human SLC5A8
PurificationProtein A Purified
Concentration1 ug/ul
Intended UseFor research use only. Not intended for diagnostic or therapeutic use.
Application InfoWB: 1:100~1000
IHC-P: 1:100~500
Fluorescent-IHC: 1:50~200
Publications

Impaired butyrate absorption in the proximal colon, low serum butyrate and diminished central effects of butyrate on blood pressure in spontaneously hypertensive rats. Acta Physiol (Oxf). 226, e13256 (2019). 30656835

Description
Gene SymbolSLC5A8
Gene Full Namesolute carrier family 5 member 8
Alias SymbolsAIT;apical iodide transporter;electrogenic sodium monocarboxylate cotransporter;SMCT;SMCT1;sodium iodide-related cotransporter;sodium-coupled monocarboxylate transporter 1;solute carrier family 5 (iodide transporter), member 8;solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8;Solute carrier family 5 member 8.
NCBI Gene Id160728
Protein NameSodium-coupled monocarboxylate transporter 1
Description of TargetActs as an electrogenic sodium (Na(+)) and chloride (Cl-)-dependent sodium-coupled solute transporter, including transport of monocarboxylates (short-chain fatty acids including L-lactate, D-lactate, pyruvate, acetate, propionate, valerate and butyrate), lactate, mocarboxylate drugs (nicotinate, benzoate, salicylate and 5-aminosalicylate) and ketone bodies (beta-D-hydroxybutyrate, acetoacetate and alpha-ketoisocaproate), with a Na(+):substrate stoichiometry of between 4:1 and 2:1. Catalyzes passive carrier mediated diffusion of iodide. Mediates iodide transport from the thyrocyte into the colloid lumen through the apical membrane. May be responsible for the absorption of D-lactate and monocarboxylate drugs from the intestinal tract. Acts as a tumor suppressor, suppressing colony formation in colon cancer, prostate cancer and glioma cell lines. May play a critical role in the entry of L-lactate and ketone bodies into neurons by a process driven by an electrochemical Na(+) gradient and hence contribute to the maintenance of the energy status and function of neurons.
Uniprot IDQ8N695
  1. What is the species homology for "SLC5A8 Antibody (OABF01657)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Bovine|Chicken|Dog|Human|Mouse|Rat".

  2. How long will it take to receive "SLC5A8 Antibody (OABF01657)"?

    This item is available "3 to 5 business days.".

  3. What buffer format is "SLC5A8 Antibody (OABF01657)" provided in?

    This item is provided in "Liquid. Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "SLC5A8 Antibody (OABF01657)"?

    This target may also be called "AIT;apical iodide transporter;electrogenic sodium monocarboxylate cotransporter;SMCT;SMCT1;sodium iodide-related cotransporter;sodium-coupled monocarboxylate transporter 1;solute carrier family 5 (iodide transporter), member 8;solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8;Solute carrier family 5 member 8." in publications.

  5. What is the shipping cost for "SLC5A8 Antibody (OABF01657)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "SLC5A8 Antibody (OABF01657)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "SLC5A8 Antibody (OABF01657)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "SLC5A8 Antibody (OABF01657)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "SLC5A8"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "SLC5A8"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "SLC5A8"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "SLC5A8"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "SLC5A8"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "SLC5A8"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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