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- Email: info@avivasysbio.com
- $55: Antibody & Protein in US
- $55 + $25/Kit in US
- Contact us for international orders.
| Datasheets/Manuals | Printable datasheet for anti-SKP2 (OAAJ02045) antibody |
|---|
| Predicted Species Reactivity | Human |
|---|---|
| Product Format | Liquid. Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Application | WB, IHC, IF, ICC |
| Reconstitution and Storage | Store at -20C. Stable for 12 months from date of receipt. |
| Immunogen | A synthesized peptide derived from human SKP2/p45 |
| Purification | Immunogen affinity purified |
| Concentration | 1 mg/ml |
| Specificity | SKP2/p45 antibody detects endogenous levels of SKP2/p45 |
| Application Info | WB: 1:500-1:2000 IHC: 1:50-1:200 IF/ICC: 1:100-1:500 |
| Gene Symbol | SKP2 |
|---|---|
| Gene Full Name | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase |
| Alias Symbols | p45, FBL1, FLB1, FBXL1 |
| NCBI Gene Id | 6502 |
| Description of Target | SKP2 an F-box protein of the SCF (SKP1-CUL1-F- box protein) E3 ubiquitin ligase system. The F-box component of the SCF complex is responsible for recognizing different substrates for ubiquitination. The SCF E3 complex mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription. Specifically recognizes phosphorylated CDKN1B/p27kip and is involved in regulation of G1/S transition. Degradation of CDKN1B/p27kip also requires CKS1. Three alternatively-spliced isoforms have been described. |
| Uniprot ID | Q13309 |
| Molecular Weight | 47 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "SKP2 Antibody (OAAJ02045)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".
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How long will it take to receive "SKP2 Antibody (OAAJ02045)"?
This item is available "Domestic: within 2-3 week delivery | International: 2-3 weeks".
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What buffer format is "SKP2 Antibody (OAAJ02045)" provided in?
This item is provided in "Liquid. Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "SKP2 Antibody (OAAJ02045)"?
This target may also be called "p45, FBL1, FLB1, FBXL1" in publications.
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What is the shipping cost for "SKP2 Antibody (OAAJ02045)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "SKP2 Antibody (OAAJ02045)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "SKP2 Antibody (OAAJ02045)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "47 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "SKP2 Antibody (OAAJ02045)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "SKP2"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "SKP2"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "SKP2"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "SKP2"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "SKP2"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "SKP2"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
