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Catalog No: OASG06663
Size:100 uL
Price: $239.00
SKU
OASG06663
Availability: Domestic: within 2-3 weeks delivery | International: 2-3 weeks
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SKP2 Antibody - C-terminal region (OASG06663)

Datasheets/ManualsPrintable datasheet for anti-SKP2 (OASG06663) antibody
Product Info
Predicted Species ReactivityHuman
Product FormatLiquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
ClonalityPolyclonal
IsotypeIgG
HostRabbit
ApplicationWB, IHC, IF
Reconstitution and StorageStore at -20C. Avoid repeated freeze/thaw cycles.
ImmunogenSynthesized peptide derived from the C-terminal region of human Skp2 p45. Location: 340-420aa.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration1 mg/ml
SpecificitySkp2 p45 Polyclonal Antibody detects endogenous levels of Skp2 p45 protein.
Application InfoWB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000;
Gene SymbolSKP2
Gene Full NameS-phase kinase-associated protein 2, E3 ubiquitin protein ligase
Alias Symbolsp45, FBL1, FLB1, FBXL1
NCBI Gene Id6502;
Description of TargetThis gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class; in addition to an F-box, this protein contains 10 tandem leucine-rich repeats. This protein is an essential element of the cyclin A-CDK2 S-phase kinase. It specifically recognizes phosphorylated cyclin-dependent kinase inhibitor 1B (CDKN1B, also referred to as p27 or KIP1) predominantly in S phase and interacts with S-phase kinase-associated protein 1 (SKP1 or p19). In addition, this gene is established as a protooncogene causally involved in the pathogenesis of lymphomas. Alternative splicing of this gene generates three transcript variants encoding different isoforms.
Uniprot IDQ13309
Molecular Weight47 kDa
  1. What is the species homology for "SKP2 Antibody - C-terminal region (OASG06663)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".

  2. How long will it take to receive "SKP2 Antibody - C-terminal region (OASG06663)"?

    This item is available "Domestic: within 2-3 weeks delivery | International: 2-3 weeks".

  3. What buffer format is "SKP2 Antibody - C-terminal region (OASG06663)" provided in?

    This item is provided in "Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "SKP2 Antibody - C-terminal region (OASG06663)"?

    This target may also be called "p45, FBL1, FLB1, FBXL1" in publications.

  5. What is the shipping cost for "SKP2 Antibody - C-terminal region (OASG06663)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "SKP2 Antibody - C-terminal region (OASG06663)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "SKP2 Antibody - C-terminal region (OASG06663)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "47 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "SKP2 Antibody - C-terminal region (OASG06663)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "SKP2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "SKP2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "SKP2"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "SKP2"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "SKP2"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "SKP2"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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