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- $55: Antibody & Protein in US
- $55 + $25/Kit in US
- Contact us for international orders.
| Datasheets/Manuals | Printable datasheet for anti-SIRT1 (OASG06653) antibody |
|---|
| Predicted Species Reactivity | Human, Mouse |
|---|---|
| Product Format | Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Host | Rabbit |
| Application | WB |
| Reconstitution and Storage | Store at -20C. Avoid repeated freeze/thaw cycles. |
| Immunogen | Synthesized peptide derived from human SIRT1 around the phosphorylation site of S47. Location: 30-110aa. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Target Post-Translational Modification | Phospho-Ser47 |
| Specificity | Phospho-SIRT1 (S47) Polyclonal Antibody detects endogenous levels of SIRT1 protein only when phosphorylated at S47. |
| Application Info | WB 1:500-1:2000; ELISA 1:10000; |
| Gene Symbol | SIRT1 |
|---|---|
| Gene Full Name | sirtuin 1 |
| Alias Symbols | SIR2, SIR2L1, SIR2alpha |
| NCBI Gene Id | 23411; 93759; |
| Description of Target | This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. |
| Uniprot ID | Q96EB6, Q923E4 |
| Molecular Weight | 110 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "SIRT1 Antibody (Phospho-Ser47) (OASG06653)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse".
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How long will it take to receive "SIRT1 Antibody (Phospho-Ser47) (OASG06653)"?
This item is available "Domestic: within 2-3 weeks delivery | International: 2-3 weeks".
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What buffer format is "SIRT1 Antibody (Phospho-Ser47) (OASG06653)" provided in?
This item is provided in "Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "SIRT1 Antibody (Phospho-Ser47) (OASG06653)"?
This target may also be called "SIR2, SIR2L1, SIR2alpha" in publications.
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What is the shipping cost for "SIRT1 Antibody (Phospho-Ser47) (OASG06653)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "SIRT1 Antibody (Phospho-Ser47) (OASG06653)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "SIRT1 Antibody (Phospho-Ser47) (OASG06653)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "110 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "SIRT1 Antibody (Phospho-Ser47) (OASG06653)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "SIRT1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "SIRT1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "SIRT1"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "SIRT1"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "SIRT1"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "SIRT1"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
