SIGMAR1 Antibody - N-terminal region (OAAB01426)

Catalog No: OAAB01426

Size:400ul

Western blot analysis of OPRS1 (arrow) using rabbit polyclonal OPRS1 Antibody (N-term) (Cat.#OAAB01426).293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the OPRS1 gene (Lane 2) (Origene Technologies

Flow cytometric analysis of NCI-H292 cells using OPRS1 Antibody (N-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Mouse, Rat
• Product Format: Liquid PBS with 0.09% (W/V) sodium azide.
• Clonality: Polyclonal
• Isotype: Rabbit Ig
• Host: Rabbit
• Application: WB, FC, ELISA
  Cellular Location:
  Nucleus inner membrane. Nucleus outer membrane. Endoplasmic reticulum membrane. Lipid droplet. Cell junction. Cell membrane. Cell projection, growth cone Note=Targeted to lipid droplets, cholesterol and galactosylceramide-enriched domains of the endoplasmic reticulum Enriched at cell-cell communication regions, growth cone and postsynaptic structures. Localization is modulated by ligand- binding
  
  Tissue Location:
  Widely expressed with higher expression in liver, colon, prostate, placenta, small intestine, heart and pancreas. Expressed in the retina by retinal pigment epithelial cells.
• Reconstitution and Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: This OPRS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 47-81 amino acids from the N-terminal region of human OPRS1.
• Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Concentration: 2 mg/ml
• Application Info: WB: 1:1000
  FC: 1:10~50
• Other Applications Image 1 Data: Flow cytometric analysis of NCI-H292 cells using OPRS1 Antibody (N-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
• Description:
  View product citations for SIGMAR1 Antibody - N-terminal region (OAAB01426) on CiteAb

Target Info

• Gene Symbol: SIGMAR1
• Alias Symbols: SRBP, ALS16, DSMA2, OPRS1, SR-BP, SIG-1R, SR-BP1, sigma1R, hSigmaR1
• NCBI Gene Id: 10280
• Protein Name: Sigma non-opioid intracellular receptor 1
• Description of Target: OPRS1 is a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems.
• Uniprot ID: Q99720
• Protein Accession #: NP_005857.1
• Molecular Weight: 25 kDa