Catalog No: OAEB01633 (Formerly GWB-7838C7)
Size:100UG
Price: $379.00
SKU
OAEB01633
Availability: Domestic: within 1-2 week delivery | International: 1-2 weeks
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  • $55: Antibody & Protein in US
  • $55 + $25/Kit in US
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Datasheets/ManualsPrintable datasheet for SIAH1 Antibody (OAEB01633)
Product Info
Predicted Species ReactivityBovine|Dog|Human|Mouse|Rat
Product FormatSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
ClonalityPolyclonal
HostGoat
ApplicationWB
::Description: This product is expected to recognize both reported isoforms (according to NP_003022.3; NP_001006611.1)
Reconstitution and StorageAliquot and store at -20C. Minimize freezing and thawing.
ImmunogenSIAH1
PurificationAmmonium Sulfate Precipitated; Affinity Purified
Predicted Homology Based on Immunogen SequenceCow: 100%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 86%; Rat: 100%; Zebrafish: 100%
Peptide SequenceSRQTATALPTGTSKC
Concentration0.5 mg/ml
PurityPurified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Application InfoPeptide ELISA: antibody detection limit dilution 1:32000.
Western Blot: Approx 28+30kDa bands observed in Human Liver lysates (calculated MW of 31.1kDa and 34.6kDa according to NP_003022.3 and NP_001006611.1). Recommended concentration: 0.1-0.3ug/ml.
Reference* Guigon CJ, Zhao L, Lu C, Willingham MC, Cheng SY.; Regulation of beta-catenin by a novel nongenomic action of thyroid hormone beta receptor.; Mol Cell Biol. 2008 Jul;28(14):4598-608.; Pubmed 18474620
* Groenman F, Rutter M, Caniggia I, Tibboel D, Post M.; Hypoxia-inducible factors in the first trimester human lung.; J Histochem Cytochem. 2007 Apr;55(4):355-63.; Pubmed 17189520
* Iwai A, Marusawa H, Matsuzawa S, Fukushima T, Hijikata M, Reed JC, Shimotohno; K, Chiba T.; Siah-1L, a novel transcript variant belonging to the human Siah family of proteins, regulates beta-catenin activity in a p53-dependent manner.; Oncogene. 2004 Sep 30;23(45):7593-600.; Pubmed 15326481
* Susini L, Passer BJ, Amzallag-Elbaz N, Juven-Gershon T, Prieur S, Privat N, Tuynder M, Gendron MC, Israel A, Amson R, Oren M, Telerman A.; Siah-1 binds and regulates the function of Numb.; Proc Natl Acad Sci U S A. 2001 Dec 18;98(26):15067-72.; Pubmed 11752454
Gene SymbolSiah1|SIAH1|Siah1a
Gene Full Namesiah E3 ubiquitin protein ligase 1|siah E3 ubiquitin protein ligase 1A
Alias SymbolsAA982064;AI853500;BURHAS;E3 ubiquitin-protein ligase SIAH1;E3 ubiquitin-protein ligase SIAH1A;mSiah-1a;RING-type E3 ubiquitin transferase SIAH1;RING-type E3 ubiquitin transferase SIAH1A;seven in absentia 1A;seven in absentia homolog 1;seven in absentia homolog 1a;Si;SIAH;siah-1;siah-1a;SIAH1A;Sinh1a.
NCBI Gene Id140941|20437|6477
Protein NameE3 ubiquitin-protein ligase SIAH1
Uniprot IDQ8IUQ4
Protein Accession #NP_003022.3
Molecular Weight31.1; 34.6
  1. What is the species homology for "SIAH1 Antibody (OAEB01633)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Bovine|Dog|Human|Mouse|Rat".

  2. How long will it take to receive "SIAH1 Antibody (OAEB01633)"?

    This item is available "Domestic: within 1-2 week delivery | International: 1-2 weeks".

  3. What buffer format is "SIAH1 Antibody (OAEB01633)" provided in?

    This item is provided in "Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "SIAH1 Antibody (OAEB01633)"?

    This target may also be called "AA982064;AI853500;BURHAS;E3 ubiquitin-protein ligase SIAH1;E3 ubiquitin-protein ligase SIAH1A;mSiah-1a;RING-type E3 ubiquitin transferase SIAH1;RING-type E3 ubiquitin transferase SIAH1A;seven in absentia 1A;seven in absentia homolog 1;seven in absentia homolog 1a;Si;SIAH;siah-1;siah-1a;SIAH1A;Sinh1a." in publications.

  5. What is the shipping cost for "SIAH1 Antibody (OAEB01633)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "SIAH1 Antibody (OAEB01633)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "SIAH1 Antibody (OAEB01633)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "31.1; 34.6".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "SIAH1 Antibody (OAEB01633)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "Siah1|SIAH1|Siah1a"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "Siah1|SIAH1|Siah1a"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "Siah1|SIAH1|Siah1a"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "Siah1|SIAH1|Siah1a"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "Siah1|SIAH1|Siah1a"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "Siah1|SIAH1|Siah1a"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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