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OAPB00903-FITC Conjugated

OAPB00903-HRP Conjugated

OAPB00903-Biotin Conjugated

SHOC2 Antibody (OAPB00903)

Catalog#: OAPB00903
Domestic: within 1 week delivery International: 1 week
More Information
Predicted Species Reactivity Human, Mouse, Rat
Clonality Polyclonal
Host Rabbit
Application WB, IHC
:: Buffer: Antibody is supplied in PBS containing 0.02% sodium azide.
Reconstitution and Storage SHOC2 antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Replacement Item This antibody may replace item sc-123846 from Santa Cruz Biotechnology.
Immunogen The immunogen for anti-SHOC2 antibody: antibody was raised against a 21 amino acid peptide near the amino terminus of human SHOC2.
Purification Affinity chromatography purified via peptide column
Predicted Homology Based on Immunogen Sequence Human; Mouse; Rat
Blocking Peptide For anti-SHOC2 antibody is Catalog # OEPB03025
Datasheets/Manuals Printable datasheet for anti-SHOC2 antibody - OAPB00903
Application Info SHOC2 antibody can be used for detection of Shoc2 by Western blot at 1-2 ug/ml. (Optimal dilution should be determined by user)
Target Reference Selfors LM, Schutzman JL, Borland CZ, et al. Soc-2 encodes a leucine-rich repeat protein implicated in fibroblast growth factor receptor signaling. Proc. Natl. Acad. Sci. USA1998; 95:6903-8.;Sieburth DS, Sun Q, and Han M. SUR-8, a conserved Ras-binding protein with leucine-rich repeats, positively regulates Ras-mediated signaling in C. elegans. Cell1998; 94:119–130.;Rodriguez-Viciana P, Oses-Prieto J, Burlingame A, et al. A phosphatase holoenzyme comprised of Shoc2/Sur8 and the catalytic subunit of PP1 functions as an M-Ras effector to modulate Raf activity. Mol. Cell2006; 22:217-30.;Li W, Han M, and Guan KL. The leucine-rich repeat protein SUR-8 enhances MAP kinase activation and forms a complex with Ras and Raf. Genes Dev.2000; 14:895–900.
Gene Symbol SHOC2
Alias Symbols SOC2, SUR8, SIAA0862,
NCBI Gene Id 8036
Protein Name Leucine-rich repeat protein SHOC-2
Description of Target Ras-binding protein Sur-8
Swissprot Id Q9UQ13
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express SHOC2.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express SHOC2.
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