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Conjugation Options

OAPB00903 Unconjugated

OAPB00903-FITC Conjugated

OAPB00903-HRP Conjugated

SHOC2 Antibody : Biotin (OAPB00903-Biotin)

Catalog#: OAPB00903-Biotin
Domestic: within 1 week delivery | International: 1 week
More Information
Predicted Species ReactivityHuman, Mouse, Rat
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer.
ApplicationELISA, WB, IHC
::Buffer: Antibody is supplied in PBS containing 0.02% sodium azide.
Reconstitution and StorageAll conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Replacement ItemThis antibody may replace item sc-123846 from Santa Cruz Biotechnology.
ImmunogenThe immunogen for anti-SHOC2 antibody: antibody was raised against a 21 amino acid peptide near the amino terminus of human SHOC2.
PurificationAffinity chromatography purified via peptide column
Predicted Homology Based on Immunogen SequenceHuman; Mouse; Rat
Concentration1 mg/ml
Blocking PeptideFor anti-SHOC2 antibody is Catalog # OEPB03025
Datasheets/ManualsPrintable datasheet for anti-SHOC2 antibody - OAPB00903-Biotin
Application InfoSHOC2 antibody can be used for detection of Shoc2 by Western blot at 1-2 ug/ml. (Optimal dilution should be determined by user)
Target ReferenceSelfors LM, Schutzman JL, Borland CZ, et al. Soc-2 encodes a leucine-rich repeat protein implicated in fibroblast growth factor receptor signaling. Proc. Natl. Acad. Sci. USA1998; 95:6903-8.;Sieburth DS, Sun Q, and Han M. SUR-8, a conserved Ras-binding protein with leucine-rich repeats, positively regulates Ras-mediated signaling in C. elegans. Cell1998; 94:119–130.;Rodriguez-Viciana P, Oses-Prieto J, Burlingame A, et al. A phosphatase holoenzyme comprised of Shoc2/Sur8 and the catalytic subunit of PP1 functions as an M-Ras effector to modulate Raf activity. Mol. Cell2006; 22:217-30.;Li W, Han M, and Guan KL. The leucine-rich repeat protein SUR-8 enhances MAP kinase activation and forms a complex with Ras and Raf. Genes Dev.2000; 14:895–900.
Gene SymbolSHOC2
Alias SymbolsSOC2, SUR8, SIAA0862,
NCBI Gene Id8036
Protein NameLeucine-rich repeat protein SHOC-2
Description of TargetRas-binding protein Sur-8
Swissprot IdQ9UQ13
Tissue ToolFind tissues and cell lines supported by DNA array analysis to express SHOC2.
RNA SeqFind tissues and cell lines supported by RNA-seq analysis to express SHOC2.
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