SHH Recombinant Protein (OPCD06961)

Catalog No: OPCD06961

SHH Recombinant Protein (OPCD06961) using SDS-PAGE

SHH Recombinant Protein (OPCD06961) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Pro36-Ala193
  Subcellular Location: Secreted, extracellular space. Cell membrane; Lipid-ancho
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 90%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: SHH
• Gene Full Name: sonic hedgehog signaling molecule
• Alias Symbols: HHG1;HHG-1;HLP3;HPE3;MCOPCB5;shh unprocessed N-terminal signaling and C-terminal autoprocessing domains;ShhNC;SMMCI;sonic hedgehog homolog;sonic hedgehog protein;TPT;TPTPS.
• NCBI Gene Id: 6469
• Protein Name: Sonic hedgehog protein
• Description of Target: Sonic hedgehog protein: The C-terminal part of the sonic hedgehog protein precursor displays an autoproteolysis and a cholesterol transferase activity (By similarity). Both activities result in the cleavage of the full-length protein into two parts (ShhN and ShhC) followed by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated ShhN (By similarity). Both activities occur in the reticulum endoplasmic (By similarity). Once cleaved, ShhC is degraded in the endoplasmic reticulum (By similarity).
• Uniprot ID: Q15465
• Protein Accession #: NP_000184.1
• Nucleotide Accession #: NM_000193.3
• Protein Size (# AA): Pro36~Ala193
• Molecular Weight: 22kDa