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SH2B3 Recombinant Protein (Mouse) (OPCA32792)

Catalog#: OPCA32792
Domestic: within 4-6 weeks delivery | International: 4-6 weeks
More Information
Predicted Species ReactivityMouse
Product FormatLiquid
HostE. coli, yeast, insect, or mammalian cell can be selected above to determine price.
ApplicationWB, ELISA
Additional InformationFor Research Use Only.
Sterile filtering available upon request.
Low endotoxin available upon request.
Reconstitution and StorageThe shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C. Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week.
PurityGreater than 85% as determined by SDS-PAGE.
Storage BufferTris-based buffer,50% glycerol
TagThis protein may contain a N-terminal tag or C-terminal tag based on protein stability requirements.
Datasheets/ManualsPrintable datasheet for OPCA32792
Gene SymbolSH2B3
Official Gene Full NameSH2B adaptor protein 3
Alias SymbolsLnk, AI429800
NCBI Gene Id16923
Protein NameSH2B adapter protein 3
Description of TargetThis gene encodes a member of the SH2B family of adapter proteins that play an important role in T cell receptor signaling. This gene is preferentially expressed in hematopoietic stem cells, hematopoietic progenitors, pre and immature B cells, as well as megakaryocytes and mastocytes. In hematopoietic stem cells, the encoded protein is a key regulator of self-renewal, proliferation and apoptosis. Mice lacking the encoded protein exhibit pre and immature B cell expansion in spleen and the bone marrow. Alternative splicing results in multiple transcript variants encoding different isoforms.
Swissprot IdO09039
Protein Accession #NP_001293055.1
Nucleotide Accession #NM_001306126.1
Protein Size (# AA)548
Tissue ToolFind tissues and cell lines supported by DNA array analysis to express SH2B3.
RNA SeqFind tissues and cell lines supported by RNA-seq analysis to express SH2B3.
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