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SFRS10 antibody - N-terminal region (ARP40528_T100)

100 ul
$229.00
In Stock

Conjugation Options

ARP40528_T100-FITC Conjugated

ARP40528_T100-HRP Conjugated

ARP40528_T100-Biotin Conjugated

Gene Symbol:
TRA2B
NCBI Gene Id:
6434
Official Gene Full Name:
Transformer 2 beta homolog (Drosophila)
Protein Name:
Transformer-2 protein homolog beta
Swissprot Id:
P62995
Protein Accession #:
NP_004584
Nucleotide Accession #:
NM_004593
Alias Symbols:
SFRS10, SRFS10, TRAN2B, TRA2-BETA, Htra2-beta
Replacement Item:
This antibody may replace item sc-51002 from Santa Cruz Biotechnology.
Description of Target:
SFRS10 contains 1 RRM (RNA recognition motif) domain and belongs to the splicing factor SR family. It is a sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing.
Protein Size (# AA):
288
Molecular Weight:
32kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Protein A purified
Application:
IHC, WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express SFRS10.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express SFRS10.
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human SFRS10
Species Reactivity:
Cow, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat
Predicted Homology Based on Immunogen Sequence:
Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%
Complete computational species homology data:
Anti-SFRS10 (ARP40528_T100)
Peptide Sequence:
Synthetic peptide located within the following region: MSDSGEQNYGERESRSASRSGSAHGSGKSARHTPARSRSKEDSRRSRSKS
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
SUMO3; SUMO2; EED; CLK3; SRPK2; SRPK1; YWHAE; HNRNPA1; CDK6; YTHDC1; RBMX; RNPS1; SRSF10; NXF1; UBC; SRSF6; SRSF4; SRSF3; SRSF2; MAGOH; EIF4A3; BARD1; PAXIP1; PPP4R2; SF3B1; FAF2; PSIP1; GCN1L1; EIF4H; SRSF7; SRSF5; SRSF1; S100A9; RBMS2; RAN; PRKDC; NHP2L
Blocking Peptide:
For anti-TRA2B (ARP40528_T100) antibody is Catalog # AAP40528 (Previous Catalog # AAPP22295)
Datasheets/Manuals:
Printable datasheet for anti-TRA2B (ARP40528_T100) antibody
Sample Type Confirmation:

TRA2B is strongly supported by BioGPS gene expression data to be expressed in Jurkat

Target Reference:
Helmken,C., (2003) Hum. Genet. 114 (1), 11-21
Publications:

Fu, K. et al. Tra2β protein is required for tissue-specific splicing of a smooth muscle myosin phosphatase targeting subunit alternative exon. J. Biol. Chem. 287, 16575-85 (2012). IHC, WB, Cow, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat 22437831

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