SFRP1 Recombinant Protein (OPCD06926)

Catalog No: OPCD06926

Product Info

• Predicted Species Reactivity: Mouse|Mus musculus
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: <1.0EU per 1 ug (determined by the LAL method)
  Subcellular Location: Secreted
  Isoelectric Point: 9.0
  Residues: Ser32-Lys314
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 150 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: Sfrp1
• Gene Full Name: secreted frizzled-related protein 1
• Alias Symbols: 2210415K03Rik;AW011917;AW107218;AW742929;secreted frizzled-related protein 1;secreted frizzled-related sequence protein 1;sFR;sFRP-1.
• NCBI Gene Id: 20377
• Protein Name: Secreted frizzled-related protein 1
• Description of Target: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP1 decreases intracellular beta-catenin levels (By similarity). Has antiproliferative effects on vascular cells, in vitro and in vivo, and can induce, in vivo, an angiogenic response. In vascular cell cycle, delays the G1 phase and entry into the S phase. In kidney development, inhibits tubule formation and bud growth in metanephroi (By similarity). Inhibits WNT1/WNT4-mediated TCF-dependent transcription (By similarity).
• Uniprot ID: Q8C4U3
• Protein Accession #: NP_038862.2
• Nucleotide Accession #: NM_013834.3
• Protein Size (# AA): Ser32~Lys314
• Molecular Weight: 35kDa