SFN Recombinant Protein (OPCD06925)

Catalog No: OPCD06925

SFN Recombinant Protein (OPCD06925) using SDS-PAGE

SFN Recombinant Protein (OPCD06925) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Mouse|Mus musculus
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Met1-Ser249
  Subcellular Location: Cytoplasm. Nucleus. Secreted
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: Sfn
• Gene Full Name: stratifin
• Alias Symbols: 14-3-3;14-3-3 protein sigma;14-3-3 sigma protein;E;Er;Mme1;Stratifin;tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, sigma polypeptide;Ywh;Ywhas.
• NCBI Gene Id: 55948
• Protein Name: 14-3-3 protein sigma
• Description of Target: Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway. May also regulate MDM2 autoubiquitination and degradation and thereby activate p53/TP53.
• Uniprot ID: O70456
• Protein Accession #: NP_061224.2
• Nucleotide Accession #: NM_018754.2
• Protein Size (# AA): Met1~Ser248
• Molecular Weight: 33kDa