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SFN Antibody (OAAJ06663)

100 uL
$289.00
In Stock
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Predicted Species Reactivity:
Human, Mouse, Rat
Product Format:
Liquid
Clonality:
Polyclonal
Host:
Rabbit
Application:
WB, IHC
Reconstitution and Storage:
Store at +4C. For long term storage, aliquot and store at -20C. Avoid freeze/thaw cycles.
Gene Symbol:
SFN
NCBI Gene Id:
2810
Protein Name:
14-3-3 protein sigma
Swissprot Id:
P31947
Protein Accession #:
NP_006133
Nucleotide Accession #:
NM_006142
Alias Symbols:
14-3-3 protein sigma, Epithelial cell marker protein 1, HME1, Stratifin, YWHAS
Description of Target:
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway. May also regulate MDM2 autoubiquitination and degradation and thereby activate p53/TP53.
Molecular Weight:
28 kDa
Purification:
Immunogen affinity chromatography
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express SFN.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express SFN.
Immunogen:
Recombinant proteinof human SFN
Concentration:
1 mg/mL
Datasheets/Manuals:
Printable datasheet for anti-SFN (OAAJ06663) antibody

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