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SFN Antibody - middle region (OAAB14341)

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Predicted Species Reactivity:
Cow, Human, Mouse
Product Format:
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Additional Information:
Precautions: SFN Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Function: Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway (By similarity)
Cellular Location: Cytoplasm. Nucleus (By similarity). Secreted. Note=May be secreted by a non-classical secretory pathway
Tissue Location: Present mainly in tissues enriched in stratified squamous keratinizing epithelium
Reconstitution and Storage:
Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Gene Symbol:
NCBI Gene Id:
Protein Name:
14-3-3 protein sigma
Swissprot Id:
Protein Accession #:
Alias Symbols:
SFN, HME1, 14-3-3 protein sigma, Epithelial cell marker protein 1, Stratifin
Replacement Item:
This antibody may replace item sc-100638 from Santa Cruz Biotechnology.
Description of Target:
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Molecular Weight:
27774 Da
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express SFN.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express SFN.
This SFN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 120-149 amino acids from the Central region of human SFN.
Predicted Homology Based on Immunogen Sequence:
Cow; Human; Mouse
Approximately 0.5mg/ml. Actual concentration varies with each lot.
Printable datasheet for OAAB14341
Application Info:
WB: 1:1000

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