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SERPINF2 Antibody (OAGA00824)

100 ul
$329.00
In Stock
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Predicted Species Reactivity:
Human, Mouse
Product Format:
Liquid
Clonality:
Polyclonal
Isotype:
IgG
Host:
Rabbit
Application:
ICC, IF, IHC-FFPE, WB
Additional Information:
Background: This gene encodes a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. Consequently, the proper function of this gene has a major role in regulating the blood clotting pathway. Mutations in this gene result in alpha-2-plasmin inhibitor deficiency, which is characterized by severe hemorrhagic diathesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
:::
Positive Controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji, mouse liver
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Cellular Localization: Secreted
Reconstitution and Storage:
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Replacement Item:
This antibody may replace item sc-114353 from Santa Cruz Biotechnology.
Immunogen:
Recombinant fragment corresponding to a region within amino acids 188 and 453 of alpha 2 Antiplasmin (Uniprot ID#P08697)
Purification:
Purified by antigen-affinity chromatography.
Concentration:
1 mg/ml
Datasheets/Manuals:
Printable datasheet for anti-SERPINF2 antibody - OAGA00824
Application Info:
Suggested starting dilutions are as follows: WB: 1:500-1:3000, IHC-P: 1:100-1:1000 [suggested antigen retrieval using heat mediated 10mM Citrate buffer (pH6.0) or Tris-EDTA buffer (pH8.0)], ICC/IF: 1:100-1:1000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
Storage Buffer:
0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Gene Symbol:
SERPINF2
Official Gene Full Name:
Alpha-2-antiplasmin
Alias Symbols:
A2AP antibody, AAP antibody, ALPHA-2-PI antibody, API antibody, PLI antibody, SERPINF2 antibody, serpin F2 antibody, alpha-2-plasmin inhibitor antibody, alpha-2-AP antibody, alpha-2-antiplasmin antibody, "serine (or cysteine) proteinase inhibitor, clade F
NCBI Gene Id:
5345
Protein Name:
Alpha-2-antiplasmin
Swissprot Id:
P08697
Protein Accession #:
NP_000925.2
Molecular Weight:
55 kDa
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express SERPINF2.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express SERPINF2.

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