SERPINE1 Recombinant Protein (OPCD05963)

Catalog No: OPCD05963

SERPINE1 Recombinant Protein (OPCD05963) using SDS-PAGE

SERPINE1 Recombinant Protein (OPCD05963) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Rat|Rattus norvegicus
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Ser24-Pro402
  Subcellular Location: Secreted.
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: Serpine1
• Gene Full Name: serpin family E member 1
• Alias Symbols: endothelial plasminogen activator inhibitor;PAI;Pai1;PAI-1;PAI1A;Pai1aa;Planh;plasminogen activator inhibitor 1;RATPAI1A;serine (or cysteine) peptidase inhibitor, clade E, member 1;serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1;serine (or cysteine) proteinase inhibitor, clade E, member 1;serine (or cysteine) proteinase inhibitor, member 1;serpin E1;serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1.
• NCBI Gene Id: 24617
• Protein Name: Plasminogen activator inhibitor 1
• Description of Target: Serine protease inhibitor. Inhibits TMPRSS7. Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU). As PLAT inhibitor, it is required for fibrinolysis down-regulation and is responsible for the controlled degradation of blood clots. As PLAU inhibitor, it is involved in the regulation of cell adhesion and spreading. Acts as a regulator of cell migration, independently of its role as protease inhibitor. It is required for stimulation of keratinocyte migration during cutaneous injury repair. It is involved in cellular and replicative senescence (By similarity). Plays a role in alveolar type 2 cells senescence in the lung (By similarity). Is involved in the regulation of cementogenic differentiation of periodontal ligament stem cells, and regulates odontoblast differentiation and dentin formation during odontogenesis (By similarity).
• Uniprot ID: P20961
• Protein Accession #: NP_036752.1
• Nucleotide Accession #: NM_012620.1
• Protein Size (# AA): Ser24~Pro402
• Molecular Weight: 46kDa