Catalog No: OACD06322
Price: $0.00
SKU
OACD06322
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Datasheets/ManualsPrintable datasheet for SERPINA5 Antibody (OACD06322)
Product Info
Predicted Species ReactivityHuman|Rat
Product FormatLiquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
ClonalityPolyclonal
IsotypeIgG
HostRabbit
ApplicationEnzyme-linked immunosorbent assay|Immunocytochemistry|Immunohistochemistry|Immunohistochemistry-Frozen|Immunohistochemistry-Paraffin|Western blot
Reconstitution and Storage2°C to 8°C|-20°C
ImmunogenRange: Ser43 - Pro406
PurificationAffinity Purified; Protein A Purified
Concentration1 mg/ml
Preservative0.02% NaN3
SpecificityThe antibody is a rabbit polyclonal antibody raised against PCI. It has been selected for its ability to recognize PCI in immunohistochemical staining and western blotting.
FormulationPBS, pH7.4, containing 0.02% NaN3, 50% glycerol
Application DataWestern blotting: 1:50-400
Immunocytochemistry in formalin fixed cells: 1:50-500
Immunohistochemistry in formalin fixed frozen section: 1:50-500
Immunohistochemistry in paraffin section: 1:10-100
Enzyme-linked Immunosorbent Assay: 1:100-1:5,000
Optimal working dilutions must be determined by end user.
Gene SymbolSERPINA5
Gene Full Nameserpin family A member 5
Alias Symbolsacrosomal serine protease inhibitor;PAI3;PAI-3;PCI;PCI-B;PLANH3;plasma serine protease inhibitor;Plasminogen activator inhibitor 3;plasminogen activator inhibitor III;plasminogen activator inhibitor-3;PROCI;protein C inhibitor;serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5;Serpin A5;serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5.
NCBI Gene Id5104
Protein NamePlasma serine protease inhibitor
Description of TargetHeparin-dependent serine protease inhibitor acting in body fluids and secretions. Inactivates serine proteases by binding irreversibly to their serine activation site. Involved in the regulation of intravascular and extravascular proteolytic activities. Plays hemostatic roles in the blood plasma. Acts as a procoagulant and proinflammatory factor by inhibiting the anticoagulant activated protein C factor as well as the generation of activated protein C factor by the thrombin/thrombomodulin complex. Acts as an anticoagulant factor by inhibiting blood coagulation factors like prothrombin, factor XI, factor Xa, plasma kallikrein and fibrinolytic enzymes such as tissue- and urinary-type plasminogen activators. In seminal plasma, inactivates several serine proteases implicated in the reproductive system. Inhibits the serpin acrosin; indirectly protects component of the male genital tract from being degraded by excessive released acrosin. Inhibits tissue-and urinary-type plasminogen activator, prostate-specific antigen and kallikrein activities; has a control on the sperm motility and fertilization. Inhibits the activated protein C-catalyzed degradation of SEMG1 and SEMG2; regulates the degradation of semenogelin during the process of transfer of spermatozoa from the male reproductive tract into the female tract. In urine, inhibits urinary-type plasminogen activator and kallikrein activities. Inactivates membrane-anchored serine proteases activities such as MPRSS7 and TMPRSS11E. Inhibits urinary-type plasminogen activator-dependent tumor cell invasion and metastasis. May also play a non-inhibitory role in seminal plasma and urine as a hydrophobic hormone carrier by its binding to retinoic acid.
Uniprot IDP05154
Protein Accession #NP_000615.3
Nucleotide Accession #NM_000624
Molecular Weight46 kDa
  1. What is the species homology for "SERPINA5 Antibody (OACD06322)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human|Rat".

  2. How long will it take to receive "SERPINA5 Antibody (OACD06322)"?

    This item is available "Domestic: within 1-2 weeks delivery | International: within 1-2 weeks delivery".

  3. What buffer format is "SERPINA5 Antibody (OACD06322)" provided in?

    This item is provided in "Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "SERPINA5 Antibody (OACD06322)"?

    This target may also be called "acrosomal serine protease inhibitor;PAI3;PAI-3;PCI;PCI-B;PLANH3;plasma serine protease inhibitor;Plasminogen activator inhibitor 3;plasminogen activator inhibitor III;plasminogen activator inhibitor-3;PROCI;protein C inhibitor;serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5;Serpin A5;serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5." in publications.

  5. What is the shipping cost for "SERPINA5 Antibody (OACD06322)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "SERPINA5 Antibody (OACD06322)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "SERPINA5 Antibody (OACD06322)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "46 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "SERPINA5 Antibody (OACD06322)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "SERPINA5"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "SERPINA5"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "SERPINA5"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "SERPINA5"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "SERPINA5"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "SERPINA5"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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