SEMA7A Recombinant Protein (OPCD06913)

Catalog No: OPCD06913

SEMA7A Recombinant Protein (OPCD06913) using SDS-PAGE

SEMA7A Recombinant Protein (OPCD06913) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Tyr242-Arg507
  Subcellular Location: Cell membrane; Lipid-anchor, GPI-anchor; Extracellular sid
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 90%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: SEMA7A
• Gene Full Name: semaphorin 7A (John Milton Hagen blood group)
• Alias Symbols: CD108;CDw108;H-SEMA-K1;H-Sema-L;JMH;JMH blood group antigen;John Milton Hagen blood group H-Sema K1;john-Milton-Hargen human blood group Ag;sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A (JMH blood group);sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, 7A;sema K1;sema L;SEMAK1;SEMAL;semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group);semaphorin-7A;semaphorin-K1;semaphorin-L.
• NCBI Gene Id: 8482
• Protein Name: Semaphorin-7A
• Description of Target: Plays an important role in integrin-mediated signaling and functions both in regulating cell migration and immune responses. Promotes formation of focal adhesion complexes, activation of the protein kinase PTK2/FAK1 and subsequent phosphorylation of MAPK1 and MAPK3. Promotes production of proinflammatory cytokines by monocytes and macrophages. Plays an important role in modulating inflammation and T-cell-mediated immune responses. Promotes axon growth in the embryonic olfactory bulb. Promotes attachment, spreading and dendrite outgrowth in melanocytes.
• Uniprot ID: O75326
• Protein Accession #: NP_001139501.1
• Nucleotide Accession #: NM_001146029.2
• Protein Size (# AA): Tyr242~Arg507
• Molecular Weight: 34kDa