SEMA7A Recombinant Protein (OPCD06912)

Catalog No: OPCD06912

SEMA7A Recombinant Protein (OPCD06912) using SDS-PAGE

SEMA7A Recombinant Protein (OPCD06912) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Mouse|Mus musculus
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Arg318-Met566
  Subcellular Location: Cell membrane; Lipid-anchor, GPI-anchor; Extracellular si
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: Sema7a
• Gene Full Name: sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A
• Alias Symbols: 2900057C09Rik;CDw108;H-Sema K1;H-Sema-L;M-Sema-L;Se;sema K1;sema L;Semal;semaphorin-7A;semaphorin-K1;semaphorin-L.
• NCBI Gene Id: 20361
• Protein Name: Semaphorin-7A
• Description of Target: Plays an important role in integrin-mediated signaling and functions both in regulating cell migration and immune responses. Promotes formation of focal adhesion complexes, activation of the protein kinase PTK2/FAK1 and subsequent phosphorylation of MAPK1 and MAPK3. Promotes production of proinflammatory cytokines by monocytes and macrophages. Plays an important role in modulating inflammation and T-cell-mediated immune responses. Promotes axon growth in the embryonic olfactory bulb. Promotes attachment, spreading and dendrite outgrowth in melanocytes.
• Uniprot ID: Q9QUR8
• Protein Accession #: NP_035482.1
• Nucleotide Accession #: NM_011352.2
• Protein Size (# AA): Arg318~Met566
• Molecular Weight: 32kDa