Size:100 ul
Special Price $229.00 Regular Price $289.00
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ARP49583_P050
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Conjugation Options

ARP49583_P050-FITC Conjugated

ARP49583_P050-HRP Conjugated

ARP49583_P050-Biotin Conjugated

SEMA6D Antibody - N-terminal region (ARP49583_P050)

Catalog#: ARP49583_P050
Domestic: within 1-2 days delivery | International: 1-2 days
More Information
Tested Species Reactivity Human
Predicted Species Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Clonality Polyclonal
Host Rabbit
Application WB
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Replacement Item This antibody may replace item sc-367711 from Santa Cruz Biotechnology.
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human SEMA6D
Purification Affinity Purified
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Complete computational species homology data Anti-SEMA6D (ARP49583_P050)
Peptide Sequence Synthetic peptide located within the following region: VSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQHRLDFQLMLKIRDTLY
Concentration Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Blocking Peptide For anti-SEMA6D (ARP49583_P050) antibody is Catalog # AAP49583 (Previous Catalog # AAPP13108)
Datasheets/Manuals Printable datasheet for anti-SEMA6D (ARP49583_P050) antibody
Target Reference Toyofuku,T., (2004) Genes Dev. 18 (4), 435-447
Gene Symbol SEMA6D
Official Gene Full Name Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
Alias Symbols FLJ11598, KIAA1479
NCBI Gene Id 80031
Protein Name Semaphorin-6D
Description of Target Semaphorins are a large family, including both secreted and membrane associated proteins, many of which have been implicated as inhibitors or chemorepellents in axon pathfinding, fasciculation and branching, and target selection. All semaphorins possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Additional sequence motifs C-terminal to the semaphoring domain allow classification into distinct subfamilies. Results demonstrate that transmembrane semaphorins, like the secreted ones, can act as repulsive axon guidance cues. SEMA6D is a class 6 vertebrate transmembrane semaphorin that demonstrates alternative splicing. Six transcript variants have been identified and expression of the distinct encoded isoforms is thought to be regulated in a tissue- and development-dependent manner.Semaphorins are a large family, including both secreted and membrane associated proteins, many of which have been implicated as inhibitors or chemorepellents in axon pathfinding, fasciculation and branching, and target selection. All semaphorins possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Additional sequence motifs C-terminal to the semaphorin domain allow classification into distinct subfamilies. Results demonstrate that transmembrane semaphorins, like the secreted ones, can act as repulsive axon guidance cues. This gene encodes a class 6 vertebrate transmembrane semaphorin that demonstrates alternative splicing. Six transcript variants have been identified and expression of the distinct encoded isoforms is thought to be regulated in a tissue- and development-dependent manner.
Swissprot Id Q8NFY4
Protein Accession # NP_079242
Nucleotide Accession # NM_024966
Protein Size (# AA) 476
Molecular Weight 52kDa
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express SEMA6D.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express SEMA6D.
Protein Interactions PLXNA1;
  1. What is the species homology for "SEMA6D Antibody - N-terminal region (ARP49583_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish".

  2. How long will it take to receive "SEMA6D Antibody - N-terminal region (ARP49583_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "SEMA6D Antibody - N-terminal region (ARP49583_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "SEMA6D Antibody - N-terminal region (ARP49583_P050)"?

    This target may also be called "FLJ11598, KIAA1479" in publications.

  5. What is the shipping cost for "SEMA6D Antibody - N-terminal region (ARP49583_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "SEMA6D Antibody - N-terminal region (ARP49583_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "SEMA6D Antibody - N-terminal region (ARP49583_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "52kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "SEMA6D Antibody - N-terminal region (ARP49583_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "SEMA6D"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "SEMA6D"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "SEMA6D"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "SEMA6D"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "SEMA6D"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "SEMA6D"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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