SEC24D Antibody - middle region (ARP88735_P050)

Catalog No: ARP88735_P050

Host: Rabbit
Target Name: SEC24D
Sample Tissue: Human 786-0 Whole Cell lysates
Antibody Dilution: 1ug/ml

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SEC24D
• Purification: Affinity purified
• Peptide Sequence: Synthetic peptide located within the following region: LNGPGASPLPLPMYRPDGLSGPPPPNAQYQPPPLPGQTLGAGYPPQQANS
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-SEC24D (ARP88735_P050) antibody is Catalog # AAP88735

Target Info

• Gene Symbol: SEC24D
• Gene Full Name: SEC24 homolog D, COPII coat complex component
• Alias Symbols: CLCRP2
• NCBI Gene Id: 9871
• Protein Name: protein transport protein Sec24D
• Description of Target: The protein encoded by this gene is a member of the SEC24 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec24p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. This gene product is implicated in the shaping of the vesicle, and also in cargo selection and concentration. Mutations in this gene have been associated with Cole-Carpenter syndrome, a disorder affecting bone formation, resulting in craniofacial malformations and bones that break easily. Alternative splicing results in multiple transcript variants encoding different isoforms.
• Uniprot ID: O94855
• Protein Accession #: NP_001304995.1
• Nucleotide Accession #: NM_014822.2
• Protein Size (# AA): 1032
• Molecular Weight: 113 kDa