SDPR Antibody - middle region (OAAB06533)

Catalog No: OAAB06533

Size:400UL

Western blot analysis of SDR Antibody (Center) in CHO cell lysates (35ug/lane). SDR (arrow) was detected using the purified Pab.

SDR Antibody (Center) IHC analysis in formalin fixed and paraffin embedded lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the SDR Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

SDR Antibody (Center) flow cytometric analysis of NCI-H460 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Product Info

• Predicted Species Reactivity: Human
• Product Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Clonality: Polyclonal
• Isotype: Rabbit Ig
• Host: Rabbit
• Application: FC,IHC-P,WB
  Description: This SDR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 115~145 amino acids from the Central region of human SDR.
• Reconstitution and Storage: Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: This SDR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-135 amino acids from the Central region of human SDR.
• Predicted Homology Based on Immunogen Sequence: Human
• Concentration: Approximately 0.5mg/ml. Actual concentration varies with each lot.
• Application Info: WB: 1:1000
  IHC-P: 1:50~100
  FC: 1:10~50
• Other Applications Image 1 Data: SDR Antibody (Center) flow cytometric analysis of NCI-H460 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Target Info

• Gene Symbol: SDPR
• Alias Symbols: caveolae-associated protein 2, cavin-2, phosphatidylserine-binding protein, PS-p68, SDPR, SDR, serum deprivation response, serum deprivation-response protein.
• NCBI Gene Id: 8436
• Protein Name: Caveolae-associated protein 2|caveolae-associated protein 2 [Homo sapiens]
• Description of Target: Plays an important role in caveolar biogenesis and morphology. Regulates caveolae morphology by inducing membrane curvature within caveolae (PubMed:19525939). Plays a role in caveola formation in a tissue-specific manner. Required for the formation of caveolae in the lung and fat endothelia but not in the heart endothelia. Negatively regulates the size or stability of CAVIN complexes in the lung endothelial cells. May play a role in targeting PRKCA to caveolae (By similarity).
• Uniprot ID: O95810
• Protein Accession #: https://www.ncbi.nlm.nih.gov/protein/NP_004648.1
• Molecular Weight: 47173