| Product Number |
P102230_T100 |
| Product Page |
www.avivasysbio.com/nucb1-antibody-c-terminal-region-p102230-t100.html |
| Name |
NUCB1 Antibody - C-terminal region (P102230_T100) |
| Protein Size (# AA) |
461 amino acids |
| Molecular Weight |
51kDa |
| NCBI Gene Id |
4924 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
Nucleobindin 1 |
| Alias Symbols |
NUC, CALNUC |
| Peptide Sequence |
Synthetic peptide located within the following region: PAAHPEGQLKFHPDTDDVPVPAPAGDQKEVDTSEKKLLERLPEVEVPQHL |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Lin, P., et al., approved publication in the Journal of Neurochemistry. See //www.blackwell-synergy.com/loi/jnc for details (doi: 10.1111/j.1471-4159.2006.04336.x). |
| Description of Target |
Calnuc or NUCB1 belongs to the nucleobindin family. It is a major calcium-binding protein of the Golgi and is a good Golgi marker. It may be involved in calcium homeostasis. Calnuc also plays roles in regulation of levels of .-amyloid precursor protein (APP) and its proteolytic metabolites to further affect the patho/physiological functions of APP including Alzheimer's disease pathogenesis. Useful for immunohistochemistry and western blot. |
| Protein Interactions |
REL; UBC; MDM2; CTPS2; RAD23B; PRKDC; METTL1; GTF2I; CBS; XPNPEP1; WARS; PTGS2; XPO1; SET; RBL1; MYC; HIVEP1; GNAS; GNAI3; GNAI1; KLC4; PTGS1; NDN; GNAI2; GNAO1; GNAZ; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-NUCB1 (P102230_T100) antibody |
| Blocking Peptide |
For anti-NUCB1 (P102230_T100) antibody is Catalog # AAP32192 (Previous Catalog # AAPP03165) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human NUCB1 |
| Uniprot ID |
Q02818 |
| Protein Name |
Nucleobindin-1 |
| Publications |
Calnuc Function in Endosomal Sorting of Lysosomal Receptors. Traffic. 17, 416-32 (2016). 26756199 |
| Protein Accession # |
NP_006175 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_006184 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
NUCB1 |
| Predicted Species Reactivity |
Human |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Human: 100% |
| Image 1 | Human HepG2
 | Host: Rabbit
Target Name: NUCB1
Sample Tissue: Human HepG2
Antibody Dilution: 1ug/ml |
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