| Product Number |
P100992_P050 |
| Product Page |
www.avivasysbio.com/mnat1-antibody-n-terminal-region-p100992-p050.html |
| Name |
MNAT1 Antibody - N-terminal region (P100992_P050) |
| Protein Size (# AA) |
309 amino acids |
| Molecular Weight |
36kDa |
| NCBI Gene Id |
4331 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis) |
| Description |
|
| Alias Symbols |
MAT1, TFB3, CAP35, RNF66 |
| Peptide Sequence |
Synthetic peptide located within the following region: DDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGT |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Li,Y., (2007) Lung Cancer 58 (2), 171-183 |
| Description of Target |
The coenzyme NAD and its derivatives are involved in hundreds of metabolic redox reactions and are utilized in protein ADP-ribosylation, histone deacetylation, and in some Ca(2+) signaling pathways. NMNAT (EC 2.7.7.1) is a central enzyme in NAD biosynthesis, catalyzing the condensation of nicotinamide mononucleotide (NMN) or nicotinic acid mononucleotide (NaMN) with the AMP moiety of ATP to form NAD or NaAD.Cyclin-dependent kinases (CDKs), which play an essential role in cell cycle control of eukaryotic cells, are phosphorylated and thus activated by the CDK-activating kinase (CAK). CAK is a multisubunit protein that includes CDK7 (MIM 601955), cyclin H (CCNH; MIM 601953), and MAT1. MAT1 (for 'menage a trois-1') is involved in the assembly of the CAK complex.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-498 AA053721.1 1-498 499-1372 BC000820.1 489-1362 1373-1388 BU620200.1 1-16 c |
| Protein Interactions |
RPA3; RPA2; RPA1; CDK7; CDK2; MBP; CTD; CCNH; NGFRAP1; UBC; NKX3-1; USP2; SUPT5H; POLR2A; GTF2H4; GTF2H3; GTF2H1; ERCC2; tat; TRIM39; TRIM34; TRIM17; TRIM2; ICK; TRIM31; RNF41; RNF7; TRIM26; MKRN3; TRIM21; MDM4; BRCA1; TRIML1; RNF32; TRIM9; TRIM5; XBP1P1; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-MNAT1 (P100992_P050) antibody |
| Blocking Peptide |
For anti-MNAT1 (P100992_P050) antibody is Catalog # AAP31339 (Previous Catalog # AAPP02090) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human MNAT1 |
| Uniprot ID |
P51948 |
| Protein Name |
CDK-activating kinase assembly factor MAT1 |
| Sample Type Confirmation |
MNAT1 is supported by BioGPS gene expression data to be expressed in 721_B |
| Protein Accession # |
NP_002422 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_002431 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
MNAT1 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Pig, Zebrafish |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100%; Zebrafish: 100% |
| Image 1 | Human 721_B
 | WB Suggested Anti-MNAT1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: 721_B cell lysateMNAT1 is supported by BioGPS gene expression data to be expressed in 721_B |
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