Product Number |
P100956_T100 |
Product Page |
www.avivasysbio.com/pou5f1-antibody-n-terminal-region-p100956-t100.html |
Name |
POU5F1 Antibody - N-terminal region (P100956_T100) |
Protein Size (# AA) |
360 amino acids |
Molecular Weight |
39kDa |
NCBI Gene Id |
5460 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
1.0 mg/ml |
Gene Full Name |
POU class 5 homeobox 1 |
Description |
|
Alias Symbols |
OCT3, OCT4, OTF3, OTF4, OTF-3, Oct-3, Oct-4 |
Peptide Sequence |
Synthetic peptide located within the following region: PCTVTPGAVKLEKEKLEQNPEESQDIKALQKELEQFAKLLKQKRITLGYT |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Suo,G., et al., (2005) Biochem. Biophys. Res. Commun. 337 (4), 1047-1051 |
Description of Target |
POU5F1 is a POU transcription factor expressed by early embryo cells and germ cells. It determines paracrine growth factor signaling from stem cells to the trophectoderm |
Protein Interactions |
ETS2; CETN2; XPC; RAD23B; UBC; ITCH; FOXD3; WWP2; PSMD10; NCL; PURA; PPIA; POU5F1; YBX1; KRT19; KRT14; KRT10; KRT9; KRT2; KRT1; HNRNPK; HMGB1; HIST1H1T; GAPDH; FKBP7; EHMT2; AGR2; TUBB4A; EIF5B; TUBA1A; NR2F2; TRA2B; SRSF3; RPS25; RPS23; RPS19; RPL31; RPL |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-POU5F1 (P100956_T100) antibody |
Blocking Peptide |
For anti-POU5F1 (P100956_T100) antibody is Catalog # AAP31313 (Previous Catalog # AAPP02063) |
Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human POU5F1 |
Uniprot ID |
Q01860 |
Protein Name |
POU domain, class 5, transcription factor 1 |
Publications |
Kaeffer, B. et al. Non-invasive exploration of neonatal gastric epithelium by using exfoliated epithelial cells. PLoS One 6, e25562 (2011). 22028779
Li, Y. et al. BMP4-directed trophoblast differentiation of human embryonic stem cells is mediated through a dNp63+ cytotrophoblast stem cell state. Development 140, 3965-76 (2013). 24004950
Oct-4B isoform is differentially expressed in breast cancer cells: hypermethylation of regulatory elements of Oct-4A suggests an alternative promoter and transcriptional start site for Oct-4B transcription. Biosci Rep. 31, 109-15 (2011). 20433421 |
Protein Accession # |
NP_002692 |
Purification |
Protein A purified |
Nucleotide Accession # |
NM_002701 |
Tested Species Reactivity |
Human |
Gene Symbol |
POU5F1 |
Predicted Species Reactivity |
Human, Dog, Goat, Pig, Rabbit |
Application |
WB |
Predicted Homology Based on Immunogen Sequence |
Dog: 91%; Goat: 100%; Human: 100%; Pig: 84%; Rabbit: 92% |
Image 1 | Human Jurkat
| WB Suggested Anti-POU5F1 Antibody Titration: 1.25ug/ml ELISA Titer: 1:62500 Positive Control: Jurkat cell lysate |
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