| Product Number |
P100953_P050 |
| Product Page |
www.avivasysbio.com/max-antibody-n-terminal-region-p100953-p050.html |
| Name |
MAX Antibody - N-terminal region (P100953_P050) |
| Protein Size (# AA) |
151 amino acids |
| Molecular Weight |
17kDa |
| NCBI Gene Id |
4149 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
MYC associated factor X |
| Description |
|
| Alias Symbols |
bHLHd4 |
| Peptide Sequence |
Synthetic peptide located within the following region: MSDNDDIEVESDADKRAHHNALERKRRDHIKDSFHSLRDSVPSLQGEKAS |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Faiola,F., (2007) Biochem. J. 403 (3), 397-407 |
| Description of Target |
MAX is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation.The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Multiple alternatively spliced transcript variants have been described for this gene but the full length nature for some of them is unknown. The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Multiple alternatively spliced transcript variants have been described for this gene but the full-length nature for some of them is unknown. |
| Protein Interactions |
USP37; UNC45A; BANP; FBXW11; MXI1; RPL35; TUBA1A; RPL34; GABBR1; FUS; FTH1; MYC; MXD1; MGA; PLIN3; HSP90AA1; TCF3; MYCN; CPSF6; ARL6IP5; KMT2D; HNRNPH2; DYNC1H1; CSTF2; SNIP1; PPP1CC; PPP1CB; PPP1CA; USF1; PCGF6; EP400; DMAP1; WDR5; BRD8; KAT5; MNT; MAX; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-MAX (P100953_P050) antibody |
| Blocking Peptide |
For anti-MAX (P100953_P050) antibody is Catalog # AAP31308 (Previous Catalog # AAPP02058) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the n terminal region of human MAX |
| Uniprot ID |
P61244 |
| Protein Name |
Protein max |
| Sample Type Confirmation |
There is BioGPS gene expression data showing that MAX is expressed in COLO205 |
| Protein Accession # |
NP_660087 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_145112 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
MAX |
| Predicted Species Reactivity |
Human, Mouse, Rat, Dog, Zebrafish |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Dog: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 92% |
| Image 1 | Human COLO205
 | WB Suggested Anti-MAX Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: COLO205 cell lysateThere is BioGPS gene expression data showing that MAX is expressed in COLO205 |
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