LMO2 Antibody - N-terminal region (P100952_P050)

Data Sheet
 
Product Number P100952_P050
Product Page www.avivasysbio.com/lmo2-antibody-n-terminal-region-p100952-p050.html
Name LMO2 Antibody - N-terminal region (P100952_P050)
Protein Size (# AA) 158 amino acids
Molecular Weight 18kDa
NCBI Gene Id 4005
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name LIM domain only 2 (rhombotin-like 1)
Description
Alias Symbols TTG2, LMO-2, RBTN2, RHOM2, RBTNL1
Peptide Sequence Synthetic peptide located within the following region: GGGARAPEGVRAPAAGQPRATKGAPPPPGTPPPSPMSSAIERKSLDPSEE
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Yuan,W., (2008) Leukemia 22 (5), 1067-1071
Description of Target LMO2 acts with TAL1/SCL to regulate red blood cell development. LMO2 also acts with LDB1 to maintain erythroid precursors in an immature state.LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Protein Interactions ADAMTSL4; MBIP; HOOK1; TFPT; NOTCH2NL; KRTAP10-7; CCDC36; NUTM1; SPERT; FAM154A; CLHC1; KRT40; SSX2IP; CMTM5; MRFAP1L1; IFT43; C1orf94; LZTS2; TSC22D4; DBF4B; CCDC33; RINT1; NIF3L1; TRIM54; AGTRAP; ZFP64; BANP; STAT3; STAT1; SOX5; SKP1; ROCK1; REL; PRKG1;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-LMO2 (P100952_P050) antibody
Blocking Peptide For anti-LMO2 (P100952_P050) antibody is Catalog # AAP31307 (Previous Catalog # AAPP02056)
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human LMO2
Uniprot ID P25791
Protein Name Rhombotin-2
Protein Accession # NP_005565
Purification Affinity Purified
Nucleotide Accession # NM_005574
Tested Species Reactivity Human
Gene Symbol LMO2
Predicted Species Reactivity Mouse, Rat, Dog, Guinea Pig, Rabbit
Application WB
Predicted Homology Based on Immunogen Sequence Dog: 100%; Guinea Pig: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Image 1
Human kidney
WB Suggested Anti-LMO2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: Human kidney
 

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