| Product Number |
P100925_P050 |
| Product Page |
www.avivasysbio.com/gabpb2-antibody-c-terminal-region-p100925-p050.html |
| Name |
GABPB2 Antibody - C-terminal region (P100925_P050) |
| Protein Size (# AA) |
395 amino acids |
| Molecular Weight |
42kDa |
| Subunit |
beta-1 |
| NCBI Gene Id |
2553 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
GA binding protein transcription factor, beta subunit 1 |
| Description |
|
| Alias Symbols |
E4TF1, GABPB, BABPB2, E4TF1B, GABPB2, NRF2B1, NRF2B2, GABPB-1, E4TF1-47, E4TF1-53 |
| Peptide Sequence |
Synthetic peptide located within the following region: PDGQQVLTVPATDIAEETVISEEPPAKRQCIEIIENRVESAEIEEREALQ |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Sawada,J., et al., (1999) J. Biol. Chem. 274 (50), 35475-35482 |
| Description of Target |
GABPB2 is the GA-binding protein transcription factor, beta subunit. It forms a tetrameric complex with the alpha subunit, and stimulates transcription of target genes. The encoded protein may be involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. The crystal structure of a similar protein in mouse has been resolved as a ternary protein complex. |
| Protein Interactions |
FAM90A1; RBM11; RSPH14; TDRD7; POGZ; LMO4; TRAF2; SNRPB2; SNRPA; LMO1; UBC; MAGEB18; RYBP; YAF2; YY1; GABPA; IL16; DHX16; CIC; LMO3; USO1; FANCG; BAI2; HCFC1; ATF1; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-GABPB1 (P100925_P050) antibody |
| Blocking Peptide |
For anti-GABPB1 (P100925_P050) antibody is Catalog # AAP31279 (Previous Catalog # AAPP02028) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human GABPB2 |
| Uniprot ID |
Q06547 |
| Protein Name |
GA-binding protein subunit beta-1 |
| Sample Type Confirmation |
GABPB1 is supported by BioGPS gene expression data to be expressed in HepG2 |
| Protein Accession # |
NP_005245 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_005254 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
GABPB1 |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Chicken: 92% |
| Image 1 | Human HepG2
 | WB Suggested Anti-GABPB2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: HepG2 cell lysateGABPB1 is supported by BioGPS gene expression data to be expressed in HepG2 |
|
| Image 2 | Human Lung
 | Human Lung |
|
| Image 3 | Human Spleen
 | Human Spleen |
|
| Image 4 | Human Kidney
 | Lanes:
1. 40 ug human HK2 cell (kidney proximal tubular cell line) lysate
2. 40 ug H2O2 treated human HK2 Cell lysate
3. 40 ug H2O2 treated human HK2 Cell lysate
4. 40 ug H2O2 treated human HK2 Cell lysate
5. 40 ug H2O2 treated human HK2 Cell lysate
6. 40 ug H2O2 treated human HK2 Cell lysate
Primary Antibody Dilution:
1:1000
Secondary Antibody:
Goat anti-Rabbit HRP
Secondary Antibody Dilution:
1:2000
Gene Name:
GABPB2
Submitted by:
The University of Queensland, School of Medicine, Centre for Kidney Disease Research
|
|
