| Product Number |
P100908_P050 |
| Product Page |
www.avivasysbio.com/cebpa-antibody-n-terminal-region-p100908-p050.html |
| Name |
CEBPA Antibody - N-terminal region (P100908_P050) |
| Protein Size (# AA) |
358 amino acids |
| Molecular Weight |
38kDa |
| NCBI Gene Id |
1050 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
CCAAT/enhancer binding protein (C/EBP), alpha |
| Alias Symbols |
CEBP, C/EBP-alpha |
| Peptide Sequence |
Synthetic peptide located within the following region: GGICEHETSIDISAYIDPAAFNDEFLADLFQHSRQQEKAKAAVGPTGGGG |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Zhu,Q.S., et al., (2004) J. Biol. Chem. 279 (29), 29902-29910 |
| Description of Target |
CEBPA is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. It has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, CEBPA can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells. |
| Protein Interactions |
CEBPB; ZBTB16; RARA; HDAC1; BHLHE41; UBC; CEBPE; BATF2; BATF3; YY1AP1; ATF5; BATF; FOSL1; FOS; DBP; CEBPG; CEBPA; ATF4; ATF3; UBE3A; SKP2; RASGRF1; C1QBP; CDKN1A; SRA1; CDK4; PIAS1; Fbxw7; GRIN3A; RAB34; NAA16; POLR1E; MRTO4; AK5; MACF1; KAT5; AKAP9; SMC1 |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-CEBPA (P100908_P050) antibody |
| Blocking Peptide |
For anti-CEBPA (P100908_P050) antibody is Catalog # AAP31256 (Previous Catalog # AAPP02005) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human CEBPA |
| Uniprot ID |
P49715 |
| Protein Name |
CCAAT/enhancer-binding protein alpha |
| Sample Type Confirmation |
CEBPA is supported by BioGPS gene expression data to be expressed in HepG2 |
| Protein Accession # |
NP_004355 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_004364 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
CEBPA |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Guinea Pig, Pig |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Guinea Pig: 90%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100% |
| Image 1 | Human HepG2
 | WB Suggested Anti-CEBPA Antibody Titration: 0.2-1 ug/ml
Positive Control: HepG2 cell lysateCEBPA is supported by BioGPS gene expression data to be expressed in HepG2 |
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