| Product Number |
P100898_P050 |
| Product Page |
www.avivasysbio.com/yy1-antibody-middle-region-p100898-p050.html |
| Name |
YY1 Antibody - middle region (P100898_P050) |
| Protein Size (# AA) |
414 amino acids |
| Molecular Weight |
45kDa |
| NCBI Gene Id |
7528 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
YY1 transcription factor |
| Description |
|
| Alias Symbols |
DELTA, NF-E1, UCRBP, GADEVS, INO80S, YIN-YANG-1 |
| Peptide Sequence |
Synthetic peptide located within the following region: KQLAEFARMKPRKIKEDDAPRTIACPHKGCTKMFRDNSAMRKHLHTHGPR |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Gronroos,E., et al., (2004) Proc. Natl. Acad. Sci. U.S.A. 101 (33), 12165-12170 |
| Description of Target |
YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. The protein is involved in repressing and activating a diverse number of promoters. YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter, thus implicating histone modification in the function of YY1. |
| Protein Interactions |
HDAC1; SMURF2; UBC; SHFM1; RNF2; BMI1; SUZ12; RYBP; GABPB1; GABPA; PCGF2; RING1; EP300; LAMC2; SPRY1; SLC39A7; NR1H2; TESK1; RAF1; NFKB1; GRN; CRKL; ARRB1; SP1; WDHD1; ZNF24; NHP2L1; NCL; ZNF830; APP; ZNF638; EED; SMAD3; SMAD2; EZH2; SUMO1; SUMO3; INO80E; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-YY1 (P100898_P050) antibody |
| Blocking Peptide |
For anti-YY1 (P100898_P050) antibody is Catalog # AAP31246 (Previous Catalog # AAPP01991) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human YY1 |
| Uniprot ID |
P25490 |
| Protein Name |
Transcriptional repressor protein YY1 |
| Protein Accession # |
NP_003394 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_003403 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
YY1 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Zebrafish |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 92% |
| Image 1 | Human Thymus
 | WB Suggested Anti-YY1 Antibody Titration: 0.2-1 ug/ml
Positive Control: Human Thymus |
|
| Image 2 | Human Muscle
 | Human Muscle |
|
