| Product Number |
P100892_P050-HRP |
| Product Page |
www.avivasysbio.com/gtf2e1-antibody-c-terminal-region-hrp-p100892-p050-hrp.html |
| Name |
GTF2E1 Antibody - C-terminal region : HRP (P100892_P050-HRP) |
| Protein Size (# AA) |
439 amino acids |
| Molecular Weight |
49kDa |
| Subunit |
1 |
| Conjugation |
HRP: Horseradish Peroxidase |
| NCBI Gene Id |
2960 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
General transcription factor IIE, polypeptide 1, alpha 56kDa |
| Alias Symbols |
FE, TF2E1, TFIIE-A |
| Peptide Sequence |
Synthetic peptide located within the following region: VADDPIVMVAGRPFSYSEVSQRPELVAQMTPEEKEAYIAMGQRMFEDLFE |
| Product Format |
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6. |
| Reference |
Ohkuma,Y., et al., (1991) Nature 354 (6352), 398-401 |
| Description of Target |
The general transcription factor TFIIE has an essential role in eukaryotic transcription initiation together with RNA polymerase II and other general factors. Human TFIIE consists of two subunits of relative molecular mass 57,000 (TFIIE-alpha) and 34,000 (TFIIE-beta) and joins the preinitiation complex after RNA polymerase II and TFIIF. TFIIE-alpha is necessary for transcription initiation together with TFIIE-beta, and recombinant TFIIE-alpha can fully replace the natural subunit in an in vitro transcription assay. Its sequence contains several interesting structural motifs (leucine repeat, zinc finger and helix-turn-helix) and sequence similarities to bacterial sigma factors that suggest direct involvement in the regulation of transcription initiation |
| Protein Interactions |
UBC; AARSD1; ACBD3; XPO5; SH3GLB2; OXR1; NSUN2; RPUSD2; SNF8; EFTUD2; TTC1; SH3GL1; SARS; HARS; SRPK2; TCEA1; GTF2H1; GTF2E2; CDK7; APP; tat; GTF2F1; ELAVL1; ZSCAN1; ZBTB9; TRIM15; PCBD2; TRIM29; CBFA2T2; IKBKG; ATF7IP; TAF6; GTF2B; TRIM24; SND1; GTF2H4; |
| Reconstitution and Storage |
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding. |
| Datasheets/Manuals |
Printable datasheet for anti-GTF2E1 (P100892_P050-HRP) antibody |
| Blocking Peptide |
For anti-GTF2E1 (P100892_P050-HRP) antibody is Catalog # AAP31240 (Previous Catalog # AAPP01985) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human GTF2E1 |
| Uniprot ID |
P29083 |
| Protein Name |
General transcription factor IIE subunit 1 |
| Protein Accession # |
NP_005504 |
| Nucleotide Accession # |
NM_005513 |
| Gene Symbol |
GTF2E1 |
| Predicted Species Reactivity |
Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100% |
| Image 1 | |
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