| Product Number |
P100852_P050 |
| Product Page |
www.avivasysbio.com/mef2c-antibody-middle-region-p100852-p050.html |
| Name |
MEF2C Antibody - middle region (P100852_P050) |
| Protein Size (# AA) |
473 amino acids |
| Molecular Weight |
51kDa |
| NCBI Gene Id |
4208 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Myocyte enhancer factor 2C |
| Description |
|
| Alias Symbols |
DEL5q14.3, C5DELq14.3 |
| Peptide Sequence |
Synthetic peptide located within the following region: PPSALSQLGACTSTHLSQSSNLSLPSTQSLNIKSEPVSPPRDRTTTPSRY |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Nagel,S., (2008) Leukemia 22 (3), 600-607 |
| Description of Target |
MEF2C is a transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. MEF2C controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. MEF2C may also be involved in neurogenesis and in the development of cortical architecture. Isoform 3 and isoform 4, which lack the repressor domain, are more active than isoform 1 and isoform 2. |
| Protein Interactions |
PLA2G12A; UBC; ASCL1; SUMO1; HDAC7; HDAC5; HDAC4; MYOD1; IFRD1; NCOA2; SIRT1; HDAC9; COPS5; YWHAZ; SPTBN1; MAPK7; EPAS1; MAPK14; VGLL2; VGLL4; TWIST2; GATA4; SOX18; EP300; SMAD2; MEF2D; MEF2C; NOTCH1; TEAD1; SP1; CCNB1; CDK1; CSNK2A1; MYOG; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-MEF2C (P100852_P050) antibody |
| Blocking Peptide |
For anti-MEF2C (P100852_P050) antibody is Catalog # AAP31211 (Previous Catalog # AAPP01956) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the middle region of human MEF2C |
| Uniprot ID |
Q06413 |
| Protein Name |
Myocyte-specific enhancer factor 2C |
| Protein Accession # |
NP_002388 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_002397 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
MEF2C |
| Predicted Species Reactivity |
Human, Mouse, Rat, Dog, Horse, Pig, Rabbit, Zebrafish |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100% |
| Image 1 | Human COLO205
 | WB Suggested Anti-MEF2C Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: COLO205 cell lysate |
|
