| Product Number |
P100837_P050 |
| Product Page |
www.avivasysbio.com/gcm1-antibody-c-terminal-region-p100837-p050.html |
| Name |
GCM1 Antibody - C-terminal region (P100837_P050) |
| Protein Size (# AA) |
436 amino acids |
| Molecular Weight |
49kDa |
| NCBI Gene Id |
8521 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Glial cells missing homolog 1 (Drosophila) |
| Description |
|
| Alias Symbols |
GCMA, hGCMa |
| Peptide Sequence |
Synthetic peptide located within the following region: DFNSYVQSPAYHSPQEDPFLFTYASHPHQQYSLPSKSSKWDFEEEMTYLG |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Chuang,H.C., et al., (2006) (er) Nucleic Acids Res. 34 (5), 1459-1469 |
| Description of Target |
GCM1 is a DNA-binding protein with a gcm-motif (glial cell missing motif). GCM1 is a homolog of the Drosophila glial cells missing gene (gcm). This protein binds to the GCM-motif (A/G)CCCGCAT, a novel sequence among known targets of DNA-binding proteins. |
| Protein Interactions |
FBXW2; UBC; SENP1; CAMK1; SUMO1; DUSP23; CREBBP; HDAC5; HDAC4; HDAC3; HDAC1; CUL1; SKP1; UBE2I; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-GCM1 (P100837_P050) antibody |
| Blocking Peptide |
For anti-GCM1 (P100837_P050) antibody is Catalog # AAP31193 (Previous Catalog # AAPP01936) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human GCM1 |
| Uniprot ID |
Q9NP62 |
| Protein Name |
Chorion-specific transcription factor GCMa |
| Publications |
Drewlo, S., Czikk, M., Baczyk, D., Lye, S. & Kingdom, J. Glial cell missing-1 mediates over-expression of tissue inhibitor of metalloproteinase-4 in severe pre-eclamptic placental villi. Hum. Reprod. 26, 1025-34 (2011). 21406447 |
| Protein Accession # |
NP_003634 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_003643 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
GCM1 |
| Predicted Species Reactivity |
Human, Dog, Horse, Rabbit |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Dog: 90%; Horse: 92%; Human: 100%; Rabbit: 81% |
| Image 1 | Human HepG2
 | WB Suggested Anti-GCM1 Antibody Titration: 0.2-1 ug/ml
Positive Control: HepG2 cell lysate |
|
