| Product Number |
P100816_P050 |
| Product Page |
www.avivasysbio.com/nr2f2-antibody-n-terminal-region-p100816-p050.html |
| Name |
NR2F2 Antibody - N-terminal region (P100816_P050) |
| Protein Size (# AA) |
414 amino acids |
| Molecular Weight |
45kDa |
| NCBI Gene Id |
7026 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Nuclear receptor subfamily 2, group F, member 2 |
| Description |
|
| Alias Symbols |
ARP1, ARP-1, CHTD4, NF-E3, SRXX5, SVP40, COUPTF2, COUPTFB, TFCOUP2, COUPTFII |
| Peptide Sequence |
Synthetic peptide located within the following region: KVGMRREAVQRGRMPPTQPTHGQFALTNGDPLNCHSYLSGYISLLLRAEP |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Sato,Y., (2003) J. Clin. Endocrinol. Metab. 88 (7), 3415-3420 |
| Description of Target |
NR2F2, an orphan member of the nuclear hormone receptor superfamily, acts as a transcriptional repressor by antagonizing the functions of other nuclear hormone receptors and by actively silencing transcription. However, in certain contexts, NR2F2 stimulates transcription directly. NR2F2, MyoD and p300 interact in a competitive manner, and that increasing amounts of NR2F2 have the ability to reduce the interaction between myoD and p300 invitro. NR2F2 post-transcriptionally regulates myoD activity/function, and that crosstalk between orphan nuclear receptors and the myogenic bHLH proteins has functional consequences for differentiation. |
| Protein Interactions |
NSD1; BCL11A; NR2F2; BIK; SETD7; FAM46A; HIPK3; UBC; TFAP4; Cebpb; SMARCAD1; NR2F6; POU5F1; NR3C1; PHB2; TRIP4; PIAS1; BCL11B; TRIM24; EP300; SQSTM1; HDAC1; NCOR2; MYOD1; LCK; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-NR2F2 (P100816_P050) antibody |
| Blocking Peptide |
For anti-NR2F2 (P100816_P050) antibody is Catalog # AAP31163 (Previous Catalog # AAPS22105) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human NR2F2 |
| Uniprot ID |
P24468 |
| Protein Name |
COUP transcription factor 2 |
| Publications |
Déjardin, J. & Kingston, R. E. Purification of proteins associated with specific genomic Loci. Cell 136, 175-86 (2009). 19135898 |
| Sample Type Confirmation |
NR2F2 is supported by BioGPS gene expression data to be expressed in HEK293T |
| Protein Accession # |
NP_066285 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_021005 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
NR2F2 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Pig, Rabbit, Sheep, Zebrafish |
| Application |
IHC, WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 92%; Dog: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Sheep: 92%; Zebrafish: 92% |
| Image 1 | Human Lung
 | Rabbit Anti-NR2F2 Antibody
Catalog Number: P100816
Paraffin Embedded Tissue: Human alveolar cell
Cellular Data: Epithelial cells of renal tubule
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X |
|
| Image 2 | 293T, Human stomach
 | Host: Rabbit
Target: NR2F2
Positive control (+): 293T (2T)
Negative control (-): Human stomach (ST)
Antibody concentration: 1ug/ml |
|
| Image 3 | Human Fetal Liver
 | Host: Rabbit
Target Name: NR2F2
Sample Tissue: Human Fetal Liver
Antibody Dilution: 1.0ug/ml |
|
| Image 4 | Human Lung
 | Rabbit Anti-NR2F2 antibody
Catalog Number: P100816
Paraffin Embedded Tissue: Human Lung
cell Cellular Data: alveolar cell
Antibody Concentration: 4.0-8.0 ug/ml
Magnification: 400X |
|
