| Product Number |
P100779_T100 |
| Product Page |
www.avivasysbio.com/rela-antibody-n-terminal-region-p100779-t100.html |
| Name |
RELA Antibody - N-terminal region (P100779_T100) |
| Protein Size (# AA) |
551 amino acids |
| Molecular Weight |
60kDa |
| NCBI Gene Id |
5970 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
1.0 mg/ml |
| Gene Full Name |
V-rel reticuloendotheliosis viral oncogene homolog A (avian) |
| Description |
|
| Alias Symbols |
p65, CMCU, NFKB3 |
| Peptide Sequence |
Synthetic peptide located within the following region: VEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPTIKINGYTGPG |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reference |
Ruben, S.M., et al., (1991) Science 251 (5000) 1490-1493. |
| Description of Target |
p65 is a subunit of the nuclear factor kappa-B, a second messenger, which activates the transcription of a number of genes in multiple tissues. The inhibitory effect of I-kappa-B upon NF-kappa-B in the cytoplasm is exerted primarily through the interaction with p65. p65 shows a weak DNA-binding site which could contribute directly to DNA binding in the NF-kappa-B complex. |
| Protein Interactions |
GAN; CCND1; ABCA1; UBC; TCF4; SRSF7; RELA; REL; PRKDC; PLG; PEX1; NFKB2; NFKB1; MUC3A; KRT5; REV1; TXN2; FBXW11; IL1RN; IKBKB; HSPA5; HDAC1; EP300; CREBBP; MAP3K8; CHEK1; CDKN2A; CDK4; SPATA31A3; POTEJ; POTEE; PIWIL4; DIS3L2; DCD; IKBKG; CHUK; PLA2G4A; ST |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-RELA (P100779_T100) antibody |
| Blocking Peptide |
For anti-RELA (P100779_T100) antibody is Catalog # AAP31111 (Previous Catalog # AAPP01850) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the N terminal region of human RELA |
| Uniprot ID |
Q04206 |
| Protein Name |
Transcription factor p65 |
| Protein Accession # |
NP_068810 |
| Purification |
Protein A purified |
| Nucleotide Accession # |
NM_021975 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
RELA |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Guinea Pig, Horse, Zebrafish |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 92% |
| Image 1 | Human HepG2
 | WB Suggested Anti-RELA Antibody Titration: 1.0ug/ml
ELISA Titer: 1:62500
Positive Control: HepG2 cell lysate |
|
| Image 2 | Human 786-0 Whole Cell
 | Host: Rabbit
Target Name: RELA
Sample Tissue: Human 786-0 Whole Cell
Antibody Dilution: 0.2ug/ml |
|
