Product Number |
P100732_P050 |
Product Page |
www.avivasysbio.com/sox8-antibody-c-terminal-region-p100732-p050.html |
Name |
SOX8 Antibody - C-terminal region (P100732_P050) |
Protein Size (# AA) |
446 amino acids |
Molecular Weight |
47kDa |
NCBI Gene Id |
30812 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
0.5 mg/ml |
Gene Full Name |
SRY (sex determining region Y)-box 8 |
Description |
|
Alias Symbols |
MGC24837 |
Peptide Sequence |
Synthetic peptide located within the following region: ASPTETGPPRPHIKTEQPSPGHYGDQPRGSPDYGSCSGQSSATPAAPAGP |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Wissmuller,S., (2006) (er) Nucleic Acids Res. 34 (6), 1735-1744 |
Description of Target |
SOX8 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. It may act as a transcriptional activator after forming a protein complex with other proteins. This protein may be involved in brain development and function. Haploinsufficiency for this protein may contribute to the mental retardation found in haemoglobin H-related mental retardation (ART-16 syndrome).This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein may be involved in brain development and function. Haploinsufficiency for this protein may contribute to the mental retardation found in haemoglobin H-related mental retardation (ART-16 syndrome). |
Protein Interactions |
JAM2; PIDD1; NOD1; UBC; MMP1; SOX2; HOXC11; UTF1; PAX3; OLIG2; HHEX; POU3F3; TCF12; DLX5; SP1; NR5A1; JUN; POU5F1; EGR2; CEBPA; |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-SOX8 (P100732_P050) antibody |
Blocking Peptide |
For anti-SOX8 (P100732_P050) antibody is Catalog # AAP31043 (Previous Catalog # AAPP01776) |
Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human SOX8 |
Uniprot ID |
P57073 |
Protein Name |
Transcription factor SOX-8 |
Protein Accession # |
NP_055402 |
Purification |
Affinity Purified |
Nucleotide Accession # |
NM_014587 |
Tested Species Reactivity |
Human |
Gene Symbol |
SOX8 |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse |
Application |
WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 92%; Dog: 92%; Guinea Pig: 85%; Horse: 92%; Human: 100%; Mouse: 78%; Rat: 85% |
Image 1 | Human HeLa
| WB Suggested Anti-SOX8 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:12500 Positive Control: Hela cell lysate |
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