SOX8 Antibody - C-terminal region (P100732_P050)

Data Sheet
 
Product Number P100732_P050
Product Page www.avivasysbio.com/sox8-antibody-c-terminal-region-p100732-p050.html
Name SOX8 Antibody - C-terminal region (P100732_P050)
Protein Size (# AA) 446 amino acids
Molecular Weight 47kDa
NCBI Gene Id 30812
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name SRY (sex determining region Y)-box 8
Description
Alias Symbols MGC24837
Peptide Sequence Synthetic peptide located within the following region: ASPTETGPPRPHIKTEQPSPGHYGDQPRGSPDYGSCSGQSSATPAAPAGP
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Wissmuller,S., (2006) (er) Nucleic Acids Res. 34 (6), 1735-1744
Description of Target SOX8 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. It may act as a transcriptional activator after forming a protein complex with other proteins. This protein may be involved in brain development and function. Haploinsufficiency for this protein may contribute to the mental retardation found in haemoglobin H-related mental retardation (ART-16 syndrome).This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein may be involved in brain development and function. Haploinsufficiency for this protein may contribute to the mental retardation found in haemoglobin H-related mental retardation (ART-16 syndrome).
Protein Interactions JAM2; PIDD1; NOD1; UBC; MMP1; SOX2; HOXC11; UTF1; PAX3; OLIG2; HHEX; POU3F3; TCF12; DLX5; SP1; NR5A1; JUN; POU5F1; EGR2; CEBPA;
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-SOX8 (P100732_P050) antibody
Blocking Peptide For anti-SOX8 (P100732_P050) antibody is Catalog # AAP31043 (Previous Catalog # AAPP01776)
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human SOX8
Uniprot ID P57073
Protein Name Transcription factor SOX-8
Protein Accession # NP_055402
Purification Affinity Purified
Nucleotide Accession # NM_014587
Tested Species Reactivity Human
Gene Symbol SOX8
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse
Application WB
Predicted Homology Based on Immunogen Sequence Cow: 92%; Dog: 92%; Guinea Pig: 85%; Horse: 92%; Human: 100%; Mouse: 78%; Rat: 85%
Image 1
Human HeLa
WB Suggested Anti-SOX8 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:12500
Positive Control: Hela cell lysate
 

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