| Product Number |
P100726_P050 |
| Product Page |
www.avivasysbio.com/nr3c2-antibody-c-terminal-region-p100726-p050.html |
| Name |
NR3C2 Antibody - C-terminal region (P100726_P050) |
| Protein Size (# AA) |
867 amino acids |
| Molecular Weight |
94kDa |
| NCBI Gene Id |
4306 |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Concentration |
0.5 mg/ml |
| Gene Full Name |
Nuclear receptor subfamily 3, group C, member 2 |
| Description |
|
| Alias Symbols |
MR, MCR, MLR, NR3C2VIT |
| Peptide Sequence |
Synthetic peptide located within the following region: VSDLLEFCFYTFRESHALKVEFPAMLVEIISDQLPKVESGNAKPLYFHRK |
| Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Description of Target |
NR3C2 is a receptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol. It binds to mineralocorticoid response elements (MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels. |
| Protein Interactions |
RABAC1; RXRA; HSP90AA1; ACSL1; UBC; SRC; PPP5C; PPID; FKBP5; FKBP4; STUB1; AIP; TRIM24; NRIP1; DNAJC7; CAND1; SUMO1; UBE2I; EIF3I; PROX1; PIAS1; PIAS3; HSPA4; PTGES3; AR; NR3C1; ACTA1; ACTG1; |
| Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for anti-NR3C2 (P100726_P050) antibody |
| Blocking Peptide |
For anti-NR3C2 (P100726_P050) antibody is Catalog # AAP31009 (Previous Catalog # AAPP01742) |
| Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human NR3C2 |
| Uniprot ID |
B0ZBF5 |
| Protein Name |
Mineralocorticoid receptor Ensembl ENSP00000423510 |
| Protein Accession # |
NP_001159576 |
| Purification |
Affinity Purified |
| Nucleotide Accession # |
NM_001166104 |
| Tested Species Reactivity |
Human |
| Gene Symbol |
NR3C2 |
| Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Horse |
| Application |
WB |
| Predicted Homology Based on Immunogen Sequence |
Cow: 92%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100% |
| Image 1 | Human PANC1
 | WB Suggested Anti-NR3C2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:12500
Positive Control: PANC1 cell lysate |
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