Product Number |
P100639_T100 |
Product Page |
www.avivasysbio.com/fos-antibody-c-terminal-region-p100639-t100.html |
Name |
FOS Antibody - C-terminal region (P100639_T100) |
Protein Size (# AA) |
380 amino acids |
Molecular Weight |
41kDa |
NCBI Gene Id |
2353 |
Host |
Rabbit |
Clonality |
Polyclonal |
Concentration |
1.0 mg/ml |
Gene Full Name |
FBJ murine osteosarcoma viral oncogene homolog |
Description |
|
Alias Symbols |
p55, AP-1, C-FOS |
Peptide Sequence |
Synthetic peptide located within the following region: CTPSCTAYTSSFVFTYPEADSFPSCAAAHRKGSSSNEPSSDSLSSPTLLA |
Product Format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reference |
Pan,X., et al., (2005) Biochem. Biophys. Res. Commun. 337 (4), 1052-1058 |
Description of Target |
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death. |
Protein Interactions |
Psma4; CENPO; LMO3; ARFGAP1; USF2; USF1; PSMC5; PRKAA2; JUNB; JUN; GNG11; NQO1; ATF2; AQP1; LUZP4; CYTH4; CREB5; ABL1; CLU; ATP5I; APP; MTERF4; ANP32E; ARL6IP4; COPS4; CABP1; ZNF133; SET; NEFM; MAP1B; JUND; HSPA1A; MAF; FOS; DDIT3; CEBPG; CEBPE; CEBPA; AT |
Reconstitution and Storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for anti-FOS (P100639_T100) antibody |
Blocking Peptide |
For anti-FOS (P100639_T100) antibody is Catalog # AAP30915 (Previous Catalog # AAPP01639) |
Immunogen |
The immunogen is a synthetic peptide directed towards the C terminal region of human FOS |
Uniprot ID |
P01100 |
Protein Name |
Proto-oncogene c-Fos |
Protein Accession # |
NP_005243 |
Purification |
Protein A purified |
Nucleotide Accession # |
NM_005252 |
Tested Species Reactivity |
Human, Rat |
Gene Symbol |
FOS |
Predicted Species Reactivity |
Human, Mouse, Rat, Cow, Dog, Pig, Sheep |
Application |
WB |
Predicted Homology Based on Immunogen Sequence |
Cow: 100%; Dog: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100%; Sheep: 100% |
Image 1 | Human HepG2
| WB Suggested Anti-FOS Antibody Titration: 1.25ug/ml ELISA Titer: 1:312500 Positive Control: HepG2 cell lysate |
|
Image 2 | Rat Liver
| Host: Rat Target Name: FOS Sample Tissue: Rat Liver Antibody Dilution: 1ug/ml |
|