FOS Antibody - middle region (P100626_P050)

Data Sheet
 
Product Number P100626_P050
Product Page www.avivasysbio.com/fos-antibody-middle-region-p100626-p050.html
Name FOS Antibody - middle region (P100626_P050)
Protein Size (# AA) 380 amino acids
Molecular Weight 41kDa
NCBI Gene Id 2353
Host Rabbit
Clonality Polyclonal
Concentration 0.5 mg/ml
Gene Full Name FBJ murine osteosarcoma viral oncogene homolog
Description
Alias Symbols p55, AP-1, C-FOS
Peptide Sequence Synthetic peptide located within the following region: MSVASLDLTGGLPEVATPESEEAFTLPLLNDPEPKPSVEPVKSISSMELK
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reference Seldeen,K.L., (2008) Arch. Biochem. Biophys. 473 (1), 48-60
Description of Target The Fos family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. The family members are leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Protein Interactions Psma4; CENPO; LMO3; ARFGAP1; USF2; USF1; PSMC5; PRKAA2; JUNB; JUN; GNG11; NQO1; ATF2; AQP1; LUZP4; CYTH4; CREB5; ABL1; CLU; ATP5I; APP; MTERF4; ANP32E; ARL6IP4; COPS4; CABP1; ZNF133; SET; NEFM; MAP1B; JUND; HSPA1A; MAF; FOS; DDIT3; CEBPG; CEBPE; CEBPA; AT
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for anti-FOS (P100626_P050) antibody
Blocking Peptide For anti-FOS (P100626_P050) antibody is Catalog # AAP30916 (Previous Catalog # AAPP01640)
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human FOS
Uniprot ID P01100
Protein Name Proto-oncogene c-Fos
Protein Accession # NP_005243
Purification Affinity Purified
Nucleotide Accession # NM_005252
Tested Species Reactivity Human
Gene Symbol FOS
Predicted Species Reactivity Human, Mouse, Rat, Cow, Dog, Pig, Sheep
Application WB
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 100%; Human: 100%; Mouse: 92%; Pig: 100%; Rat: 92%; Sheep: 100%
Image 1
Human 293T
WB Suggested Anti-FOS Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: 293T cell lysate
Image 2
Human DLD1 Whole Cell
Host: Rabbit
Target Name: FOS
Sample Tissue: Human DLD1 Whole Cell
Antibody Dilution: 1ug/ml
 

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