| Product Number |
OPPA02625 |
| Product Page |
www.avivasysbio.com/aasdhppt-protein-oppa02625.html |
| Name |
AASDHPPT Protein (OPPA02625) |
| Protein Size (# AA) |
Recombinant amino acids |
| NCBI Gene Id |
60496 |
| Host |
E. Coli |
| Purity |
Greater than 95.0% as determined by SDS-PAGE. |
| Alias Symbols |
ACPS, LYS2, LYS5, CGI-80, AASD-PPT |
| Peptide Sequence |
MGSSHHHHHH SSGLVPRGSH MEGVRWAFSC GTWLPSRAEW LLAVRSIQPE EKERIGQFVF ARDAKAAMAG RLMIRKLVAE KLNIPWNHIR LQRTAKGKPV LAKDSSNPYP NFNFNISHQG DYAVLAAEPE LQVGIDIMKT SFPGRGSIPE FFHIMKRKFT NKEWETIRSF KDEWTQLDMF YRNWALKESF IKAIGVGLGF ELQRLEFDLS PLNLDIGQVY KETRLFLDGE EEKEWAFEES KIDEHHFVAV ALRKPDGSRH QDVPSQDDSK PTQRQFTILN FNDLMSSAVP MTPEDPSFWD CFCFTEEIPI RNGTKS. |
| Product Format |
The AASDHPPT solution (1 mg/ml) contains 20mM Tris-HCl Buffer (pH 8.0), 1mM DTT and 10% Glycerol. Physical appearance: Sterile Filtered colorless solution. |
| Description of Target |
Recombinant Human Aminoadipate-Semialdehyde Dehydrogenase-Phosphopantetheinyl Transferase |
| Reconstitution and Storage |
AASDHPPT should be stored desiccated below -18C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for OPPA02625 |
| Additional Information |
Product Introduction: AASDHPPT is a member of the P-Pant transferase superfamily. AASDHPPT catalyzes the post-translational modification of target proteins by phosphopantetheine and can transfer the 4'-phosphopantetheine moiety from coenzyme A to a serine residue of a broad range of acceptors, such as the acyl carrier domain of FASN (in vitro). AASDHPPT is similar to Saccharomyces cerevisiae LYS5, which is required for the activation of the alpha-aminoadipate dehydrogenase in the biosynthetic pathway of lysine. AASDHPPT is found in the heart, skeletal muscle, placenta, testis, brain, pancreas, liver and kidney. It's been suggested that defects in the human AASDHPPT gene result in pipecolic acidemia.
Product Description: AASDHPPT Human Recombinant fused with a 21 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 316 amino acids (14-309 a.a.) and having a molecular mass of 36.4kDa. The AASDHPPT is purified by proprietary chromatographic techniques. |
| Uniprot ID |
Q9NRN7 |
| Protein Name |
L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase |
| Protein Accession # |
NP_056238.2 |
| Gene Symbol |
AASDHPPT |
| Predicted Species Reactivity |
Human |
| Image 1 | |
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