Product Number |
OPPA02453 |
Product Page |
www.avivasysbio.com/gm-csf-k9-protein-oppa02453.html |
Name |
GM CSF K9 Protein (OPPA02453) |
Protein Size (# AA) |
Recombinant amino acids |
NCBI Gene Id |
403923 |
Host |
E. Coli |
Purity |
Greater than 96.0% as determined by: 1. Analysis by RP-HPLC 2. Analysis by SDS-PAGE. |
Alias Symbols |
GM-CSF |
Peptide Sequence |
APTRSPTLVT RPSQHVDAIQ EALSLLNNSN DVTAVMNKAV KVVSEVFDPEGPTCLETRLQ LYKEGLQGSL TSLKNPLTMM ANHYKQHCPP TPESPCATQNINFKSFKENL KDFLFNIPFD CWKPVKK. |
Product Format |
GMCSF was lyophilized after extensive dialysis against 1x PBS pH= 7.4. Physical appearance: Sterile Filtered White lyophilized (freeze-dried) powder. |
Description of Target |
Recombinant Canine Granulocyte Macrophage-Colony Stimulating Factor |
Reconstitution and Storage |
Reconstitution: It is recommended to reconstitute the lyophilized GMCSF in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions. Storage: Lyophilized GMCSF although stable at room temperature for 3 weeks, should be stored desiccated below -18C. Upon reconstitution GMCSF should be stored at 4C between 2-7 days and for future use below -18C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. |
Datasheets/Manuals |
Printable datasheet for OPPA02453 |
Additional Information |
Biological Activity: The ED50 as calculated by the dose-dependant stimulation of the proliferation of human TF1 erythroleukemic cells is typically 1-4 ng/ml. |
Additional Information |
Product Introduction: GMCSF is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13.GM-CSF stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. Product Description: GMCSF k9 Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 128 amino acids and having a molecular mass of 14.2 kDa. GM-CSF is purified by proprietary chromatographic techniques. |
Uniprot ID |
P48749 |
Protein Name |
Granulocyte-macrophage colony-stimulating factor |
Protein Accession # |
NP_001003245.1 |
Gene Symbol |
GMCSF k9 |
Predicted Species Reactivity |
Dog |
Image 1 | GM CSF K9 Protein (OPPA02453)
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