FHIT Protein (OPPA02301)

Data Sheet
 
Product Number OPPA02301
Product Page www.avivasysbio.com/fhit-protein-oppa02301.html
Name FHIT Protein (OPPA02301)
Protein Size (# AA) Recombinant amino acids
Molecular Weight 18 kDa
Tag C-terminal His Tag
NCBI Gene Id 2272
Host E. Coli
Purity Greater than 95% as determined by SDS-PAGE.
Concentration 1 mg/ml
Alias Symbols FRA3B, AP3Aase
Peptide Sequence MSFRFGQHLI KPSVVFLKTE LSFALVNRKP VVPGHVLVCP LRPVERFHDL RPDEVADLFQ TTQRVGTVVE KHFHGTSLTF SMQDGPEAGQ TVKHVHVHVL PRKAGDFHRN DSIYEELQKH DKEDFPASWR SEEEMAAEAA ALRVYFQLEH HHHHH.
Product Format Liquid 20mM Tris-HCl (pH 8) & 10% glycerol
Physical Appearance: Sterile filtered colorless solution
Description of Target FHIT enzyme cleaves adenosine 5'' PPP 5'' A to yield AMP and ADP. FHIT gene includees the regular fragile site FRA3B on chromosome 3. Alterations and deletions of the FHIT gene are highly linked to the genesis and establishment of human tumors of the lung, cervix, breast, colon, stomach and pancreas. In normal cells, FHIT functions as a tumor suppressor and physically relates with ubiquitin conjugating enzyme 9. FHIT Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 155 amino acids (1-147 a.a.).
Reconstitution and Storage Store at 4C if entire vial will be used within 2-4 weeks. Store frozen at -20C for longer periods of time. For long term storage, it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for OPPA02301
Uniprot ID P49789
Protein Name Bis(5'-adenosyl)-triphosphatase
Protein Accession # NP_001159715.1
Purification Purified by standard chromatography
Gene Symbol FHIT
Predicted Species Reactivity Human
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