| Product Number |
OPPA01409 |
| Product Page |
www.avivasysbio.com/a-actinin-alpha-actinin-protein-oppa01409.html |
| Name |
a-Actinin - Alpha Actinin Protein (OPPA01409) |
| NCBI Gene Id |
373918 |
| Host |
Chicken Gizzard |
| Purity |
Greater than 95.0% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. |
| Alias Symbols |
Alpha-actinin-1, Alpha-actinin cytoskeletal isoform, Non-muscle alpha-actinin-1, F-actin cross-linking protein, ACTN1, a-Actinin, Actinin Alpha |
| Product Format |
The protein was lyophilized from a 1mg/ml solution containing 10mM Tris acetate buffer pH 7.6, 0.1mM EDTA, 2mM DTT, and 20mM NaCl. Physical appearance: Sterile Filtered White lyophilized (freeze-dried) powder. |
| Description of Target |
Alpha Actinin |
| Reconstitution and Storage |
Lyophilized a-Actinin although stable at room temperature for 3 weeks, should be stored desiccated below -18C. Upon reconstitution a-Actinin should be stored at 4C between 2-7 days and for future use below -18C. For long term storage it is recommended to add a carrier protein (0. 1% HSA or BSA). Please prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for OPPA01409 |
| Additional Information |
Solubility: It is recommended to reconstitute the lyophilized a-Actinin in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions. |
| Application Info |
Protein standard in 1D and 2D SDS gelelectrophoresisImmunoassays Immunization. |
| Additional Information |
Product Introduction: ACTN1 encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments.
Product Description: Ultra pure Alpha Actinin having a Molecular mass of 95,000 dalton. |
| Uniprot ID |
P05094 |
| Protein Name |
Alpha-actinin-1 |
| Protein Accession # |
NP_989458.1 |
| Gene Symbol |
AlphaActinin |
| Image 1 | |
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