| Product Number |
OPPA01202 |
| Product Page |
www.avivasysbio.com/aprotinin-aprotinin-protein-oppa01202.html |
| Name |
Aprotinin - Aprotinin Protein (OPPA01202) |
| Molecular Weight |
6512 Da |
| NCBI Gene Id |
404172 |
| Concentration |
1 mg/ml (prior to lyoph) |
| Source |
Bovine Lung |
| Alias Symbols |
BPI, BPTI |
| Product Format |
Lyophilized. Sterile filtered white powder with no additives. |
| Description of Target |
Aprotinin inhibits the activity of several proteolytic enzymes such as chymotrypsin, kallikrein, plasmin and trypsin. Aprotinin is present in blood and in most tissues, with a high concentration in lung. Aprotinin inhibits pro-inflammatory cytokine release and maintains glycoprotein homeostasis. In platelets, aprotinin reduces glycoprotein loss (e.g., GpIb, GpIIb/IIIa), while in granulocytes it prevents the expression of pro-inflammatory adhesive glycoproteins (e.g., CD11b). |
| Reconstitution and Storage |
Reconstitution: It is recommended to reconstitute the lyophilized Aprotinin in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Storage: Lyophilized Aprotinin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution, Aprotinin should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. |
| Datasheets/Manuals |
Printable datasheet for OPPA01202 |
| Additional Information |
Chemical Formula: C284H432N84O79S7 |
| Biological Activity |
6,660 KIU (Kallikrein Inactivator Units) per mg, 3.4 pH.Eur.U/mg. |
| Uniprot ID |
P00974 |
| Protein Name |
Pancreatic trypsin inhibitor |
| Gene Symbol |
Aprotinin |
| Image 1 | |
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