CILP Recombinant Protein (OPCD02224)

Data Sheet
 
Product Number OPCD02224
Product Page www.avivasysbio.com/cilp-recombinant-protein-opcd02224.html
Name CILP Recombinant Protein (OPCD02224)
Protein Size (# AA) Pro604~His864 amino acids
Molecular Weight 60kDa
Tag N-terminal His and GST Tag
Conjugation Unconjugated
NCBI Gene Id 214425
Host E.coli
Purity > 95%
Concentration 200 ug/mL (prior to lyoph)
Source E.coli
Gene Full Name cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
Alias Symbols 9830114D16;C130036G17Rik;cartilage intermediate layer protein 1;CILP-1.
Product Format Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Description of Target Probably plays a role in cartilage scaffolding. May act by antagonizing TGF-beta1 (TGFB1) and IGF1 functions. Has the ability to suppress IGF1-induced proliferation and sulfated proteoglycan synthesis, and inhibits ligand-induced IGF1R autophosphorylation. May inhibit TGFB1-mediated induction of cartilage matrix genes via its interaction with TGFB1. Overexpression may lead to impair chondrocyte growth and matrix repair and indirectly promote inorganic pyrophosphate (PPi) supersaturation in aging and osteoarthritis cartilage (By similarity).
Reconstitution and Storage 2°C to 8°C|-80°C
Datasheets/Manuals Printable datasheet for CILP Recombinant Protein (OPCD02224)
Additional Information Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
Additional Information Residues: Pro604-His864
Additional Information Subcellular Location: Secreted, extracellular space, extracellular matrix
Uniprot ID Q66K08
Protein Name Cartilage intermediate layer protein 1
Protein Accession # NP_775561.1
Nucleotide Accession # NM_173385.2
Gene Symbol Cilp
Predicted Species Reactivity Mouse|Mus musculus
Application Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Image 1
SDS-PAGE
CILP Recombinant Protein (OPCD02224) using SDS-PAGE
 

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