| Product Number |
OPCD00996 |
| Product Page |
www.avivasysbio.com/aatf-recombinant-protein-opcd00996.html |
| Name |
AATF Recombinant Protein (OPCD00996) |
| Protein Size (# AA) |
Ser237~Gln523 amino acids |
| Molecular Weight |
44kDa |
| Tag |
N-terminal His Tag |
| Conjugation |
Unconjugated |
| NCBI Gene Id |
114512 |
| Host |
E.coli |
| Purity |
> 95% |
| Concentration |
200 ug/mL (prior to lyoph) |
| Source |
E.coli |
| Gene Full Name |
apoptosis antagonizing transcription factor |
| Alias Symbols |
Apoptosis-antagonizing transcription factor;Ded;protein AATF. |
| Product Format |
Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose. |
| Description of Target |
May function as a general inhibitor of the histone deacetylase HDAC1. Binding to the pocket region of RB1 may displace HDAC1 from RB1/E2F complexes, leading to activation of E2F target genes and cell cycle progression. Conversely, displacement of HDAC1 from SP1 bound to the CDKN1A promoter leads to increased expression of this CDK inhibitor and blocks cell cycle progression. May negatively regulate the pro-apoptotic activity of DAPK3/ZIPK. Can act cooperatively with TSG101 to stimulate AR mediated transcription activation (By similarity). May negatively regulate the pro-apoptotic activity of DAPK3/ZIPK. Can act cooperatively with TSG101 to stimulate AR mediated transcription activation. |
| Reconstitution and Storage |
2°C to 8°C|-80°C |
| Datasheets/Manuals |
Printable datasheet for AATF Recombinant Protein (OPCD00996) |
| Additional Information |
Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method) |
| Additional Information |
Residues: Ser237-Gln523 |
| Additional Information |
Subcellular Location: Nucleus |
| Uniprot ID |
Q9QYW0 |
| Protein Name |
Protein AATF |
| Protein Accession # |
NP_446172.1 |
| Nucleotide Accession # |
NM_053720.1 |
| Gene Symbol |
Aatf |
| Predicted Species Reactivity |
Rat|Rattus norvegicus |
| Application |
Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot |
| Image 1 | SDS-PAGE
 | AATF Recombinant Protein (OPCD00996) using SDS-PAGE |
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